CAMK_MKNK2 (MAP kinase-interacting serine/threonine-protein kinase 2)

Total number of chains: 17
Active chains: 2
Uniprot: MKNK2_HUMAN
Kinase Domain Residues: 83 - 368
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 10 58.8% 9HRCA
DFGin BLAminus 2 11.8% AF-Q9HBH9-K1A
DFGin None 2 11.8% 2AC5A
DFGin BLBminus 1 5.9% 8XFMA
DFGout BBAminus 1 5.9% 2AC3A
DFGout None 1 5.9% 6JLRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MKNK2 AF-Q9HBH9-K1A Q9HBH9 75 376 465.0 No_ligand No_ligand Active DFGin 6.3927 14.3642 BLAminus -141.02, 178.86 65.04, 73.59 -89.93, 20.18 286.81, 82.92 -64.09, -30.08 in-in in 9.1358 Saltbr-in 2.8038 HRD-in -77.22, -47.35 66.72, -4.74 in-in-in SNCiii in-in ActLoopNT-in 3.0955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.82, 171.77 APE9-dihe-na 99.55, -179.55 APE8-dihe-in -82.75, 130.0 APE8-rot-in 306.39 APE67-dihe-in -68.27, -19.61 -55.07, -38.24 APE12-dist-in 9.182 APE11-dist-in 11.3713 APE10-dist-in 5.8716 APE9-dist-in 3.6864 None None None AF2 -1.0 1.0 1.0 A 302.0 302.0 0 35 35 0 [[83, 368]] 1.0 AF-Q9HBH9-K1 CAMK_MKNK2_HUMAN CAMK 3.1e-78 268.6 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 AF-Q9HBH9-K3A Q9HBH9 75 376 465.0 No_ligand No_ligand Active DFGin 6.371 14.5207 BLAminus -141.97, -178.36 57.69, 78.48 -93.77, 17.96 290.64, 88.53 -63.76, -30.47 in-in in 8.8654 Saltbr-in 2.6971 HRD-in -75.8, -44.73 66.37, -11.7 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.19, 164.07 APE9-dihe-na 129.41, -179.44 APE8-dihe-in -84.02, 126.95 APE8-rot-in 303.13 APE67-dihe-in -69.33, -27.45 -56.26, -30.53 APE12-dist-in 9.2167 APE11-dist-in 11.3066 APE10-dist-in 5.8277 APE9-dist-in 3.2523 None None None AF2 -1.0 1.0 1.0 A 302.0 302.0 0 35 35 0 [[83, 368]] 1.0 AF-Q9HBH9-K3 CAMK_MKNK2_HUMAN CAMK 3.1e-78 268.6 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 8XFMA Q9HBH9 73 372 465.0 A1LU6:401 Type1 Inactive DFGin 6.5434 14.4239 BLBminus -141.64, 163.71 80.1, 63.55 -77.34, 168.74 321.53, 116.48 -77.87, 130.1 in-in in 9.2252 Saltbr-in 2.9197 HRD-in -71.0, -61.21 78.15, -10.69 in-out-out SNCioo out-out ActLoopNT-out 6.8966 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, -154.37 APE9-dihe-na -73.11, -20.45 APE8-dihe-out -69.11, -29.69 APE8-rot-in 292.97 APE67-dihe-in -59.37, -26.22 -40.2, -50.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 27.2133 APE9-dist-out 34.1139 None None None XRAY 2.6 0.193 0.254 A 314.0 276.0 24 35 16 19 [[83, 368]] 1.0 8xfm CAMK_MKNK2_HUMAN CAMK 3.6e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 2HW7A Q9HBH9 72 371 465.0 STU:60031 Type1 Inactive DFGin 4.9051 14.1234 BLBplus -153.19, 172.78 68.05, 27.15 -77.7, 175.81 23.89, 67.82 81.52, 999.0 in-in in 8.9926 Saltbr-in 2.9032 HRD-in -73.6, -55.95 77.37, -18.0 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 26.54 APE8-dihe-out -84.42, -14.4 APE8-rot-in 301.04 APE67-dihe-in -61.16, -21.76 -49.65, -47.42 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.4696 D228G None None XRAY 2.71 0.203 0.246 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 2hw7 CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CJ5A Q9HBH9 72 371 465.0 F4G:60402 Type1 Inactive DFGin 4.7212 14.2032 BLBplus -162.46, 172.43 68.97, 30.76 -76.79, 173.57 37.4, 97.79 -151.49, 999.0 in-in in 9.9389 Saltbr-in 3.5355 HRD-in -85.28, -52.54 74.74, -9.69 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -59.25 APE8-dihe-out -54.97, 8.52 APE8-rot-in 320.15 APE67-dihe-in -67.19, -16.85 -67.87, -43.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.247 D228G None None XRAY 2.8 0.207 0.28 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cj5 CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CJEA Q9HBH9 72 371 465.0 F4A:60402 Type1 Inactive DFGin 4.6562 13.3692 BLBplus -135.12, 164.67 64.72, 50.18 -93.68, 150.09 30.98, 104.33 -115.11, 999.0 in-in in 9.4692 Saltbr-in 2.7212 HRD-in -83.21, -42.27 66.73, -84.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na -75.59, 34.67 APE9-dihe-na -138.63, -69.77 APE8-dihe-out -59.09, 21.68 APE8-rot-in 331.33 APE67-dihe-in -64.12, -22.88 -64.01, -54.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.7399 D228G None None XRAY 3.36 0.216 0.316 A 316.0 271.0 29 35 14 21 [[83, 368]] 1.0 6cje CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CJHA Q9HBH9 72 371 465.0 ET8:60402 Type1 Inactive DFGin 4.8621 14.0007 BLBplus -163.44, 173.91 47.68, 57.36 -118.08, 146.56 54.32, 92.71 -139.3, 999.0 in-in in 9.6151 Saltbr-in 3.3 HRD-in -72.5, -44.87 70.72, -73.24 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -55.5 APE8-dihe-out -62.49, 8.61 APE8-rot-in 321.82 APE67-dihe-in -61.68, -26.95 -73.68, -46.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 34.5346 D228G None None XRAY 3.6 0.187 0.261 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjh CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CJWA Q9HBH9 72 371 465.0 FYV:60402 Type1 Inactive DFGin 4.8854 13.265 BLBplus -155.3, 166.66 68.02, 41.47 -103.48, 123.65 39.27, 92.5 -89.55, 999.0 out-in out 10.091 Saltbr-in 3.5322 HRD-in -71.91, -49.9 72.02, -61.49 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -70.7 APE8-dihe-out -58.3, 42.51 APE8-rot-in 334.2 APE67-dihe-in -73.39, -0.56 -86.79, -46.03 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.8135 D228G None None XRAY 3.38 0.18 0.248 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjw CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CJYA Q9HBH9 72 371 465.0 F4J:60402 Type1 Inactive DFGin 4.8006 13.7575 BLBplus -154.88, -177.71 54.06, 44.35 -96.42, 111.8 42.68, 99.17 -48.45, 999.0 in-in in 9.8543 Saltbr-in 2.9851 HRD-in -85.02, -55.03 68.85, -9.51 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -36.22 APE8-dihe-out -71.64, 1.19 APE8-rot-in 286.89 APE67-dihe-in -63.89, -16.21 -70.76, -43.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.714 D228G None None XRAY 3.05 0.242 0.308 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjy CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CK3A Q9HBH9 72 371 465.0 F67:60402 Type1 Inactive DFGin 4.9031 13.4689 BLBplus -158.08, 174.24 55.4, 53.37 -96.71, 164.55 22.89, 102.09 -125.13, 999.0 in-in in 9.8113 Saltbr-in 3.0932 HRD-in -85.04, -45.19 73.56, -88.78 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -45.63 APE8-dihe-out -65.46, -8.47 APE8-rot-in 285.66 APE67-dihe-in -67.8, -18.3 -53.92, -45.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 34.2609 D228G None None XRAY 2.9 0.193 0.263 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6ck3 CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CK6A Q9HBH9 72 371 465.0 N45:60402 Type1 Inactive DFGin 5.0784 13.3512 BLBplus -147.46, 171.42 56.17, 82.44 -123.11, 136.87 19.42, 90.66 -82.91, 999.0 in-in in 9.2893 Saltbr-in 2.779 HRD-in -66.93, -56.03 82.26, -61.18 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -30.6 APE8-dihe-out -62.51, 3.48 APE8-rot-in 325.1 APE67-dihe-in -64.79, -29.92 -81.58, -40.53 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.4127 D228G None None XRAY 3.32 0.225 0.273 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6ck6 CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6CKIA Q9HBH9 72 371 465.0 FZJ:60402 Type1 Inactive DFGin 4.906 14.0131 BLBplus -158.13, 175.12 62.02, 67.85 -118.81, 174.83 30.52, 91.37 122.46, 999.0 in-in in 9.6628 Saltbr-in 2.7798 HRD-in -69.16, -49.33 64.07, -14.51 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -26.8 APE8-dihe-out -71.51, -6.98 APE8-rot-in 274.96 APE67-dihe-in -61.16, -23.54 -52.51, -42.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 31.9691 D228G None None XRAY 2.95 0.193 0.257 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cki CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 9HRCA Q9HBH9 72 375 465.0 A1IWO:60403 Type1 Inactive DFGin 4.8675 13.3468 BLBplus -154.96, -179.97 42.22, 54.03 -101.3, 153.38 52.79, 80.06 62.52, 47.61 in-in in 9.3096 Saltbr-in 2.9174 HRD-in -76.24, -61.12 74.46, 6.01 in-out-out SNCioo out-out ActLoopNT-out 7.6786 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 70.21, 173.07 APE9-dihe-na 68.52, -73.43 APE8-dihe-out -79.52, -4.64 APE8-rot-in 300.02 APE67-dihe-in -62.63, -31.13 -55.09, -47.82 APE12-dist-out 25.8911 APE11-dist-out 28.6428 APE10-dist-out 32.77 APE9-dist-out 34.691 D228G None None XRAY 3.161 0.186 0.243 A 316.0 282.0 22 35 19 16 [[83, 368]] 1.0 9hrc CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 2AC5A Q9HBH9 72 370 465.0 No_ligand No_ligand Inactive DFGin 5.9629 14.24 None 179.06, 141.31 141.75, -84.88 81.59, -68.22 316.67, 112.33 -126.47, 999.0 in-in in 9.4123 Saltbr-in 2.689 HRD-in -78.97, -46.18 65.28, 3.22 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na -146.04, 164.66 APE9-dihe-na -132.94, -20.66 APE8-dihe-out -93.96, 15.45 APE8-rot-out 50.08 APE67-dihe-in -55.42, -30.57 -62.55, -42.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.5744 D228G None None XRAY 3.2 0.306 0.306 A 316.0 274.0 25 35 14 21 [[83, 368]] 1.0 2ac5 CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 8P9BA Q9HBH9 72 369 465.0 X8K:60402 Type1 Inactive DFGin 5.876 13.7919 None -150.06, 169.8 73.67, 48.24 -60.02, 999.0 327.08, 142.95 999.0, 999.0 in-in in 9.5716 Saltbr-in 2.6981 HRD-in -79.87, -54.07 80.13, -12.9 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -48.5 APE8-rot-none 999.0 APE67-dihe-in -71.68, -12.3 -89.2, -5.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D228G None None XRAY 2.59 0.211 0.264 A 316.0 262.0 36 35 10 25 [[83, 368]] 1.0 8p9b CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 2AC3A Q9HBH9 72 369 465.0 No_ligand No_ligand Inactive DFGout 11.0201 7.1232 BBAminus -144.36, -174.67 -154.75, 105.61 -90.27, 11.32 289.21, 125.39 -131.94, 29.93 in-in in 9.371 Saltbr-in 2.7663 HRD-in -70.15, -60.67 83.27, -9.8 in-out-out SNCioo out-out ActLoopNT-out 12.1992 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 133.03 APE9-dihe-na 78.46, -48.67 APE8-dihe-out -91.52, -13.56 APE8-rot-in 298.19 APE67-dihe-in -56.32, -28.69 -63.96, -41.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 34.0331 APE9-dist-out 33.8699 None None None XRAY 2.1 0.254 0.254 A 316.0 275.0 23 35 16 19 [[83, 368]] 1.0 2ac3 CAMK_MKNK2_HUMAN CAMK 3.7e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 6JLRA Q9HBH9 72 369 465.0 BV9:60401 Type1 Inactive DFGout 15.4317 7.6997 None -145.25, -178.49 -142.94, 102.98 -73.51, -56.94 178.41, 94.87 -80.42, 66.98 in-in in 9.6409 Saltbr-in 2.4069 HRD-in -68.02, -56.93 58.34, 18.29 in-out-out SNCioo out-out ActLoopNT-out 11.8655 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -168.74 APE8-dihe-in -96.92, 75.28 APE8-rot-out 61.76 APE67-dihe-in -57.14, -25.83 -100.5, -25.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 32.1322 None None None XRAY 2.901 0.3 0.351 A 316.0 267.0 31 35 15 20 [[83, 368]] 1.0 6jlr CAMK_MKNK2_HUMAN CAMK 3.7e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2

CAMK_MKNK2 (MAP kinase-interacting serine/threonine-protein kinase 2)

Total number of chains: 17
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 10 58.8% 9HRCA
DFGin BLAminus 2 11.8% AF-Q9HBH9-K1A
DFGin None 2 11.8% 2AC5A
DFGin BLBminus 1 5.9% 8XFMA
DFGout BBAminus 1 5.9% 2AC3A
DFGout None 1 5.9% 6JLRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MKNK2 MKNK2_HUMAN AF-Q9HBH9-K1A Q9HBH9 75 376 465.0 No_ligand No_ligand Active DFGin 6.3927 14.3642 BLAminus -141.02, 178.86 65.04, 73.59 -89.93, 20.18 286.81, 82.92 -64.09, -30.08 in-in in 9.1358 Saltbr-in 2.8038 HRD-in -77.22, -47.35 66.72, -4.74 in-in-in SNCiii in-in ActLoopNT-in 3.0955 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -154.82, 171.77 APE9-dihe-na 99.55, -179.55 APE8-dihe-in -82.75, 130.0 APE8-rot-in 306.39 APE67-dihe-in -68.27, -19.61 -55.07, -38.24 APE12-dist-in 9.182 APE11-dist-in 11.3713 APE10-dist-in 5.8716 APE9-dist-in 3.6864 None None None AF2 -1.0 1.0 1.0 A 302.0 302.0 0 35 35 0 [[83, 368]] 1.0 AF-Q9HBH9-K1 Homo sapiens CAMK_MKNK2_HUMAN CAMK 3.1e-78 268.6 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN AF-Q9HBH9-K3A Q9HBH9 75 376 465.0 No_ligand No_ligand Active DFGin 6.371 14.5207 BLAminus -141.97, -178.36 57.69, 78.48 -93.77, 17.96 290.64, 88.53 -63.76, -30.47 in-in in 8.8654 Saltbr-in 2.6971 HRD-in -75.8, -44.73 66.37, -11.7 in-in-in SNCiii in-in ActLoopNT-in 2.9507 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -161.19, 164.07 APE9-dihe-na 129.41, -179.44 APE8-dihe-in -84.02, 126.95 APE8-rot-in 303.13 APE67-dihe-in -69.33, -27.45 -56.26, -30.53 APE12-dist-in 9.2167 APE11-dist-in 11.3066 APE10-dist-in 5.8277 APE9-dist-in 3.2523 None None None AF2 -1.0 1.0 1.0 A 302.0 302.0 0 35 35 0 [[83, 368]] 1.0 AF-Q9HBH9-K3 Homo sapiens CAMK_MKNK2_HUMAN CAMK 3.1e-78 268.6 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 8XFMA Q9HBH9 73 372 465.0 A1LU6:401 Type1 Inactive DFGin 6.5434 14.4239 BLBminus -141.64, 163.71 80.1, 63.55 -77.34, 168.74 321.53, 116.48 -77.87, 130.1 in-in in 9.2252 Saltbr-in 2.9197 HRD-in -71.0, -61.21 78.15, -10.69 in-out-out SNCioo out-out ActLoopNT-out 6.8966 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, -154.37 APE9-dihe-na -73.11, -20.45 APE8-dihe-out -69.11, -29.69 APE8-rot-in 292.97 APE67-dihe-in -59.37, -26.22 -40.2, -50.99 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 27.2133 APE9-dist-out 34.1139 None None None XRAY 2.6 0.193 0.254 A 314.0 276.0 24 35 16 19 [[83, 368]] 1.0 8xfm Homo sapiens CAMK_MKNK2_HUMAN CAMK 3.6e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 2HW7A Q9HBH9 72 371 465.0 STU:60031 Type1 Inactive DFGin 4.9051 14.1234 BLBplus -153.19, 172.78 68.05, 27.15 -77.7, 175.81 23.89, 67.82 81.52, 999.0 in-in in 8.9926 Saltbr-in 2.9032 HRD-in -73.6, -55.95 77.37, -18.0 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 26.54 APE8-dihe-out -84.42, -14.4 APE8-rot-in 301.04 APE67-dihe-in -61.16, -21.76 -49.65, -47.42 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.4696 D228G None None XRAY 2.71 0.203 0.246 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 2hw7 Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CJ5A Q9HBH9 72 371 465.0 F4G:60402 Type1 Inactive DFGin 4.7212 14.2032 BLBplus -162.46, 172.43 68.97, 30.76 -76.79, 173.57 37.4, 97.79 -151.49, 999.0 in-in in 9.9389 Saltbr-in 3.5355 HRD-in -85.28, -52.54 74.74, -9.69 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -59.25 APE8-dihe-out -54.97, 8.52 APE8-rot-in 320.15 APE67-dihe-in -67.19, -16.85 -67.87, -43.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.247 D228G None None XRAY 2.8 0.207 0.28 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cj5 Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CJEA Q9HBH9 72 371 465.0 F4A:60402 Type1 Inactive DFGin 4.6562 13.3692 BLBplus -135.12, 164.67 64.72, 50.18 -93.68, 150.09 30.98, 104.33 -115.11, 999.0 in-in in 9.4692 Saltbr-in 2.7212 HRD-in -83.21, -42.27 66.73, -84.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na -75.59, 34.67 APE9-dihe-na -138.63, -69.77 APE8-dihe-out -59.09, 21.68 APE8-rot-in 331.33 APE67-dihe-in -64.12, -22.88 -64.01, -54.9 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.7399 D228G None None XRAY 3.36 0.216 0.316 A 316.0 271.0 29 35 14 21 [[83, 368]] 1.0 6cje Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CJHA Q9HBH9 72 371 465.0 ET8:60402 Type1 Inactive DFGin 4.8621 14.0007 BLBplus -163.44, 173.91 47.68, 57.36 -118.08, 146.56 54.32, 92.71 -139.3, 999.0 in-in in 9.6151 Saltbr-in 3.3 HRD-in -72.5, -44.87 70.72, -73.24 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -55.5 APE8-dihe-out -62.49, 8.61 APE8-rot-in 321.82 APE67-dihe-in -61.68, -26.95 -73.68, -46.72 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 34.5346 D228G None None XRAY 3.6 0.187 0.261 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjh Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CJWA Q9HBH9 72 371 465.0 FYV:60402 Type1 Inactive DFGin 4.8854 13.265 BLBplus -155.3, 166.66 68.02, 41.47 -103.48, 123.65 39.27, 92.5 -89.55, 999.0 out-in out 10.091 Saltbr-in 3.5322 HRD-in -71.91, -49.9 72.02, -61.49 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -70.7 APE8-dihe-out -58.3, 42.51 APE8-rot-in 334.2 APE67-dihe-in -73.39, -0.56 -86.79, -46.03 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.8135 D228G None None XRAY 3.38 0.18 0.248 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjw Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CJYA Q9HBH9 72 371 465.0 F4J:60402 Type1 Inactive DFGin 4.8006 13.7575 BLBplus -154.88, -177.71 54.06, 44.35 -96.42, 111.8 42.68, 99.17 -48.45, 999.0 in-in in 9.8543 Saltbr-in 2.9851 HRD-in -85.02, -55.03 68.85, -9.51 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -36.22 APE8-dihe-out -71.64, 1.19 APE8-rot-in 286.89 APE67-dihe-in -63.89, -16.21 -70.76, -43.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.714 D228G None None XRAY 3.05 0.242 0.308 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cjy Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CK3A Q9HBH9 72 371 465.0 F67:60402 Type1 Inactive DFGin 4.9031 13.4689 BLBplus -158.08, 174.24 55.4, 53.37 -96.71, 164.55 22.89, 102.09 -125.13, 999.0 in-in in 9.8113 Saltbr-in 3.0932 HRD-in -85.04, -45.19 73.56, -88.78 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -45.63 APE8-dihe-out -65.46, -8.47 APE8-rot-in 285.66 APE67-dihe-in -67.8, -18.3 -53.92, -45.61 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 34.2609 D228G None None XRAY 2.9 0.193 0.263 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6ck3 Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CK6A Q9HBH9 72 371 465.0 N45:60402 Type1 Inactive DFGin 5.0784 13.3512 BLBplus -147.46, 171.42 56.17, 82.44 -123.11, 136.87 19.42, 90.66 -82.91, 999.0 in-in in 9.2893 Saltbr-in 2.779 HRD-in -66.93, -56.03 82.26, -61.18 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -30.6 APE8-dihe-out -62.51, 3.48 APE8-rot-in 325.1 APE67-dihe-in -64.79, -29.92 -81.58, -40.53 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.4127 D228G None None XRAY 3.32 0.225 0.273 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6ck6 Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6CKIA Q9HBH9 72 371 465.0 FZJ:60402 Type1 Inactive DFGin 4.906 14.0131 BLBplus -158.13, 175.12 62.02, 67.85 -118.81, 174.83 30.52, 91.37 122.46, 999.0 in-in in 9.6628 Saltbr-in 2.7798 HRD-in -69.16, -49.33 64.07, -14.51 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -26.8 APE8-dihe-out -71.51, -6.98 APE8-rot-in 274.96 APE67-dihe-in -61.16, -23.54 -52.51, -42.96 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 31.9691 D228G None None XRAY 2.95 0.193 0.257 A 316.0 269.0 31 35 12 23 [[83, 368]] 1.0 6cki Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 9HRCA Q9HBH9 72 375 465.0 A1IWO:60403 Type1 Inactive DFGin 4.8675 13.3468 BLBplus -154.96, -179.97 42.22, 54.03 -101.3, 153.38 52.79, 80.06 62.52, 47.61 in-in in 9.3096 Saltbr-in 2.9174 HRD-in -76.24, -61.12 74.46, 6.01 in-out-out SNCioo out-out ActLoopNT-out 7.6786 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na 70.21, 173.07 APE9-dihe-na 68.52, -73.43 APE8-dihe-out -79.52, -4.64 APE8-rot-in 300.02 APE67-dihe-in -62.63, -31.13 -55.09, -47.82 APE12-dist-out 25.8911 APE11-dist-out 28.6428 APE10-dist-out 32.77 APE9-dist-out 34.691 D228G None None XRAY 3.161 0.186 0.243 A 316.0 282.0 22 35 19 16 [[83, 368]] 1.0 9hrc Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 2AC5A Q9HBH9 72 370 465.0 No_ligand No_ligand Inactive DFGin 5.9629 14.24 None 179.06, 141.31 141.75, -84.88 81.59, -68.22 316.67, 112.33 -126.47, 999.0 in-in in 9.4123 Saltbr-in 2.689 HRD-in -78.97, -46.18 65.28, 3.22 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaooi APEdist_nnno APE10-dihe-na -146.04, 164.66 APE9-dihe-na -132.94, -20.66 APE8-dihe-out -93.96, 15.45 APE8-rot-out 50.08 APE67-dihe-in -55.42, -30.57 -62.55, -42.01 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 33.5744 D228G None None XRAY 3.2 0.306 0.306 A 316.0 274.0 25 35 14 21 [[83, 368]] 1.0 2ac5 Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 8P9BA Q9HBH9 72 369 465.0 X8K:60402 Type1 Inactive DFGin 5.876 13.7919 None -150.06, 169.8 73.67, 48.24 -60.02, 999.0 327.08, 142.95 999.0, 999.0 in-in in 9.5716 Saltbr-in 2.6981 HRD-in -79.87, -54.07 80.13, -12.9 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, -48.5 APE8-rot-none 999.0 APE67-dihe-in -71.68, -12.3 -89.2, -5.12 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 D228G None None XRAY 2.59 0.211 0.264 A 316.0 262.0 36 35 10 25 [[83, 368]] 1.0 8p9b Homo sapiens CAMK_MKNK2_HUMAN CAMK 8e-79 270.5 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 2AC3A Q9HBH9 72 369 465.0 No_ligand No_ligand Inactive DFGout 11.0201 7.1232 BBAminus -144.36, -174.67 -154.75, 105.61 -90.27, 11.32 289.21, 125.39 -131.94, 29.93 in-in in 9.371 Saltbr-in 2.7663 HRD-in -70.15, -60.67 83.27, -9.8 in-out-out SNCioo out-out ActLoopNT-out 12.1992 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_nnoo APE10-dihe-na 999.0, 133.03 APE9-dihe-na 78.46, -48.67 APE8-dihe-out -91.52, -13.56 APE8-rot-in 298.19 APE67-dihe-in -56.32, -28.69 -63.96, -41.45 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 34.0331 APE9-dist-out 33.8699 None None None XRAY 2.1 0.254 0.254 A 316.0 275.0 23 35 16 19 [[83, 368]] 1.0 2ac3 Homo sapiens CAMK_MKNK2_HUMAN CAMK 3.7e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2
MKNK2 MKNK2_HUMAN 6JLRA Q9HBH9 72 369 465.0 BV9:60401 Type1 Inactive DFGout 15.4317 7.6997 None -145.25, -178.49 -142.94, 102.98 -73.51, -56.94 178.41, 94.87 -80.42, 66.98 in-in in 9.6409 Saltbr-in 2.4069 HRD-in -68.02, -56.93 58.34, 18.29 in-out-out SNCioo out-out ActLoopNT-out 11.8655 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -168.74 APE8-dihe-in -96.92, 75.28 APE8-rot-out 61.76 APE67-dihe-in -57.14, -25.83 -100.5, -25.05 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 32.1322 None None None XRAY 2.901 0.3 0.351 A 316.0 267.0 31 35 15 20 [[83, 368]] 1.0 6jlr Homo sapiens CAMK_MKNK2_HUMAN CAMK 3.7e-78 268.3 1.0 256.0 256.0 225 226 227 229 231 113 129 133 202 204 203 205.0 277 260 255 254 253 252 251 250 249 160 MAP kinase-interacting serine/threonine-protein kinase 2

CAMK_MKNK2 (MAP kinase-interacting serine/threonine-protein kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name