CMGC_MAPK13 (Mitogen-activated protein kinase 13)

Total number of chains: 11
Active chains: 4
Uniprot: MK13_HUMAN
Kinase Domain Residues: 25 - 308
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 45.5% 8X23A
DFGin BLAminus 4 36.4% AF-O15264-K1A
DFGout BBAminus 1 9.1% 4EYJA
DFGout None 1 9.1% 5EKNA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK13 AF-O15264-K1A O15264 17 316 365.0 No_ligand No_ligand Active DFGin 6.7156 14.5713 BLAminus -112.73, 171.67 60.84, 69.32 -78.37, 12.55 287.45, 81.02 -60.04, -27.76 in-in in 9.1472 Saltbr-in 2.6571 HRD-in -73.54, -47.63 64.31, 12.91 in-in-in SNCiii in-in ActLoopNT-in 2.8598 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.35, 170.48 APE9-dihe-na 63.1, 137.4 APE8-dihe-in -59.68, 128.16 APE8-rot-in 298.25 APE67-dihe-in -69.89, -19.95 -44.43, -45.76 APE12-dist-in 11.6476 APE11-dist-in 11.1442 APE10-dist-in 6.9945 APE9-dist-in 3.1172 None None None AF2 -1.0 1.0 1.0 A 300.0 300.0 0 25 25 0 [[25, 308]] 1.0 AF-O15264-K1 CMGC_MAPK13_HUMAN CMGC 1.6e-83 286.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 AF-O15264-K3A O15264 17 316 365.0 No_ligand No_ligand Active DFGin 6.6839 14.3001 BLAminus -111.04, 172.34 64.92, 57.42 -69.43, 8.95 289.09, 83.35 -60.13, -20.96 in-in in 8.8404 Saltbr-in 2.6862 HRD-in -78.49, -48.85 66.26, 13.63 in-in-in SNCiii in-in ActLoopNT-in 2.8194 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.12, 172.36 APE9-dihe-na 60.72, 133.13 APE8-dihe-in -58.9, 131.81 APE8-rot-in 293.67 APE67-dihe-in -71.85, -18.18 -43.73, -49.48 APE12-dist-in 11.5487 APE11-dist-in 10.9643 APE10-dist-in 6.8927 APE9-dist-in 3.1102 None None None AF2 -1.0 1.0 1.0 A 300.0 300.0 0 25 25 0 [[25, 308]] 1.0 AF-O15264-K3 CMGC_MAPK13_HUMAN CMGC 1.6e-83 286.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 4MYGA O15264 15 351 365.0 No_ligand No_ligand Active DFGin 6.4891 14.351 BLAminus -125.14, 168.04 61.79, 91.1 -102.77, 31.12 289.86, 81.51 -74.54, -23.4 in-in in 9.0993 Saltbr-in 2.6557 HRD-in -74.44, -52.31 67.97, 19.0 in-in-in SNCiii in-in ActLoopNT-in 2.9364 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.9, 162.58 APE9-dihe-na 71.34, 153.33 APE8-dihe-in -81.69, 131.95 APE8-rot-in 298.26 APE67-dihe-in -67.82, -12.64 -42.96, -50.47 APE12-dist-in 11.7233 APE11-dist-in 11.259 APE10-dist-in 7.2969 APE9-dist-in 3.1551 None TPO180,PTR182 TPO180,PTR182 XRAY 2.594 0.207 0.255 A 372.0 337.0 0 25 25 0 [[25, 308]] 1.0 4myg CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 4MYGB O15264 15 351 365.0 No_ligand No_ligand Active DFGin 7.0445 14.6375 BLAminus -124.97, 166.64 60.94, 90.32 -103.91, 32.47 288.55, 77.93 -75.34, -22.85 in-in in 9.0185 Saltbr-in 2.7108 HRD-in -74.0, -52.81 68.43, 19.44 in-in-in SNCiii in-in ActLoopNT-in 2.9305 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.52, 162.84 APE9-dihe-na 72.61, 160.89 APE8-dihe-in -88.8, 134.32 APE8-rot-in 293.77 APE67-dihe-in -66.71, -13.82 -39.44, -53.02 APE12-dist-in 11.6834 APE11-dist-in 11.1202 APE10-dist-in 7.1219 APE9-dist-in 3.1464 None TPO180,PTR182 TPO180,PTR182 XRAY 2.594 0.207 0.255 B 372.0 337.0 0 25 25 0 [[25, 308]] 1.0 4myg CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 8X23A O15264 1 351 365.0 No_ligand No_ligand Inactive DFGin 4.4605 14.5711 BLBplus -108.75, 159.38 60.92, 31.98 -79.48, 152.86 61.29, 91.31 76.91, 8.49 in-out in 9.5785 Saltbr-out 4.1387 HRD-in -79.23, -65.19 81.95, -11.45 out-out-out SNCooo out-out ActLoopNT-out 9.1781 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -142.17, 156.6 APE9-dihe-na -74.19, 163.51 APE8-dihe-in -63.49, 139.71 APE8-rot-out 62.01 APE67-dihe-in -59.97, -27.66 -138.08, 36.98 APE12-dist-out 24.2187 APE11-dist-out 22.0117 APE10-dist-out 18.5952 APE9-dist-out 12.1473 None None None XRAY 1.5 0.126 0.171 A 352.0 345.0 6 25 19 6 [[25, 308]] 1.0 8x23 CMGC_MAPK13_HUMAN CMGC 2.8e-83 285.6 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 4YNOA O15264 2 351 365.0 No_ligand No_ligand Inactive DFGin 4.6408 14.5292 BLBplus -106.91, 159.82 58.83, 35.45 -83.62, 151.39 56.12, 89.43 75.59, 13.44 in-out in 9.5181 Saltbr-out 4.1995 HRD-in -78.84, -61.56 81.3, -14.44 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na 178.94, 64.59 APE9-dihe-na -68.07, 151.86 APE8-dihe-in -68.05, 140.16 APE8-rot-out 60.48 APE67-dihe-in -55.99, -28.21 -137.84, 31.53 APE12-dist-out 16.68 APE11-dist-out 20.618 APE10-dist-out 21.3409 APE9-dist-out 12.3543 None None None XRAY 1.7 0.198 0.225 A 371.0 342.0 8 25 17 8 [[25, 308]] 1.0 4yno CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 3COIA O15264 2 351 365.0 No_ligand No_ligand Inactive DFGin 5.1434 14.696 BLBplus -109.34, 158.38 67.06, 25.75 -76.24, 161.57 53.14, 88.16 69.14, 9.53 in-out in 9.3045 Saltbr-out 4.9944 HRD-in -80.05, -63.36 75.96, -9.38 out-out-out SNCooo out-out ActLoopNT-out 7.8488 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_nnoo APE10-dihe-na 999.0, -33.58 APE9-dihe-na -115.96, 123.69 APE8-dihe-out -119.11, -9.86 APE8-rot-out 59.12 APE67-dihe-out -113.05, 116.37 -126.84, 125.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.0322 APE9-dist-out 12.4015 None None None XRAY 2.09 0.208 0.242 A 353.0 342.0 8 25 17 8 [[25, 308]] 1.0 3coi CMGC_MAPK13_HUMAN CMGC 5.4e-83 284.6 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 4EYMA O15264 2 351 365.0 0RX:401 Type1 Inactive DFGin 4.589 14.2596 BLBplus -111.28, 160.93 55.5, 39.7 -81.9, 162.64 49.72, 96.13 62.24, 29.05 in-in in 8.615 Saltbr-in 2.6388 HRD-in -72.75, -50.15 76.19, -24.88 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na 173.31, 74.82 APE9-dihe-na -69.52, 150.13 APE8-dihe-in -65.84, 135.62 APE8-rot-out 59.45 APE67-dihe-in -54.22, -31.49 -134.06, 34.95 APE12-dist-none 999.0 APE11-dist-out 18.9199 APE10-dist-out 19.5099 APE9-dist-out 12.2283 None None None XRAY 2.353 0.206 0.269 A 371.0 340.0 10 25 15 10 [[25, 308]] 1.0 4eym CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 5EKOA O15264 2 351 365.0 N17:401 Type1 Inactive DFGin 4.5273 14.3954 BLBplus -108.72, 155.21 64.28, 36.89 -82.97, 147.4 52.85, 91.53 75.52, 26.34 in-in in 8.5872 Saltbr-in 2.9082 HRD-in -83.1, -57.5 81.13, -16.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -120.45, 66.93 APE9-dihe-na -76.58, 149.26 APE8-dihe-in -66.62, 135.73 APE8-rot-out 63.55 APE67-dihe-in -58.79, -27.08 -132.32, 34.84 APE12-dist-out 15.349 APE11-dist-out 18.9116 APE10-dist-out 21.0131 APE9-dist-out 12.2945 None None None XRAY 2.0 0.202 0.241 A 371.0 341.0 9 25 16 9 [[25, 308]] 1.0 5eko CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 4EYJA O15264 2 351 365.0 N61:401 Type2 Inactive DFGout 14.1412 8.9259 BBAminus -119.65, 169.45 -144.66, 93.65 -66.01, -22.87 246.34, 91.33 167.61, -135.3 in-in in 8.5521 Saltbr-in 2.6928 HRD-in -79.04, -51.35 75.59, -22.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 159.84 APE8-dihe-in -78.63, 140.7 APE8-rot-out 65.75 APE67-dihe-in -60.46, -26.97 -136.66, 39.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.5083 None None None XRAY 2.102 0.244 0.275 A 371.0 338.0 12 25 13 12 [[25, 308]] 1.0 4eyj CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 5EKNA O15264 2 351 365.0 N58:401 Type2 Inactive DFGout 13.7266 11.5016 None -126.43, 178.01 -163.99, 148.16 -168.34, 999.0 22.62, 60.64 999.0, 999.0 in-in in 8.9624 Saltbr-in 3.1478 HRD-in -73.93, -48.48 70.17, -10.09 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.38 APE8-dihe-in -75.44, 122.66 APE8-rot-out 69.9 APE67-dihe-in -66.29, -24.17 -132.85, 41.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.6621 None None None XRAY 2.594 0.22 0.273 A 371.0 336.0 14 25 11 14 [[25, 308]] 1.0 5ekn CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13

CMGC_MAPK13 (Mitogen-activated protein kinase 13)

Total number of chains: 11
Active chains: 4
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 5 45.5% 8X23A
DFGin BLAminus 4 36.4% AF-O15264-K1A
DFGout BBAminus 1 9.1% 4EYJA
DFGout None 1 9.1% 5EKNA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
MAPK13 MK13_HUMAN AF-O15264-K1A O15264 17 316 365.0 No_ligand No_ligand Active DFGin 6.7156 14.5713 BLAminus -112.73, 171.67 60.84, 69.32 -78.37, 12.55 287.45, 81.02 -60.04, -27.76 in-in in 9.1472 Saltbr-in 2.6571 HRD-in -73.54, -47.63 64.31, 12.91 in-in-in SNCiii in-in ActLoopNT-in 2.8598 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.35, 170.48 APE9-dihe-na 63.1, 137.4 APE8-dihe-in -59.68, 128.16 APE8-rot-in 298.25 APE67-dihe-in -69.89, -19.95 -44.43, -45.76 APE12-dist-in 11.6476 APE11-dist-in 11.1442 APE10-dist-in 6.9945 APE9-dist-in 3.1172 None None None AF2 -1.0 1.0 1.0 A 300.0 300.0 0 25 25 0 [[25, 308]] 1.0 AF-O15264-K1 Homo sapiens CMGC_MAPK13_HUMAN CMGC 1.6e-83 286.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN AF-O15264-K3A O15264 17 316 365.0 No_ligand No_ligand Active DFGin 6.6839 14.3001 BLAminus -111.04, 172.34 64.92, 57.42 -69.43, 8.95 289.09, 83.35 -60.13, -20.96 in-in in 8.8404 Saltbr-in 2.6862 HRD-in -78.49, -48.85 66.26, 13.63 in-in-in SNCiii in-in ActLoopNT-in 2.8194 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.12, 172.36 APE9-dihe-na 60.72, 133.13 APE8-dihe-in -58.9, 131.81 APE8-rot-in 293.67 APE67-dihe-in -71.85, -18.18 -43.73, -49.48 APE12-dist-in 11.5487 APE11-dist-in 10.9643 APE10-dist-in 6.8927 APE9-dist-in 3.1102 None None None AF2 -1.0 1.0 1.0 A 300.0 300.0 0 25 25 0 [[25, 308]] 1.0 AF-O15264-K3 Homo sapiens CMGC_MAPK13_HUMAN CMGC 1.6e-83 286.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 4MYGA O15264 15 351 365.0 No_ligand No_ligand Active DFGin 6.4891 14.351 BLAminus -125.14, 168.04 61.79, 91.1 -102.77, 31.12 289.86, 81.51 -74.54, -23.4 in-in in 9.0993 Saltbr-in 2.6557 HRD-in -74.44, -52.31 67.97, 19.0 in-in-in SNCiii in-in ActLoopNT-in 2.9364 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.9, 162.58 APE9-dihe-na 71.34, 153.33 APE8-dihe-in -81.69, 131.95 APE8-rot-in 298.26 APE67-dihe-in -67.82, -12.64 -42.96, -50.47 APE12-dist-in 11.7233 APE11-dist-in 11.259 APE10-dist-in 7.2969 APE9-dist-in 3.1551 None TPO180,PTR182 TPO180,PTR182 XRAY 2.594 0.207 0.255 A 372.0 337.0 0 25 25 0 [[25, 308]] 1.0 4myg Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 4MYGB O15264 15 351 365.0 No_ligand No_ligand Active DFGin 7.0445 14.6375 BLAminus -124.97, 166.64 60.94, 90.32 -103.91, 32.47 288.55, 77.93 -75.34, -22.85 in-in in 9.0185 Saltbr-in 2.7108 HRD-in -74.0, -52.81 68.43, 19.44 in-in-in SNCiii in-in ActLoopNT-in 2.9305 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.52, 162.84 APE9-dihe-na 72.61, 160.89 APE8-dihe-in -88.8, 134.32 APE8-rot-in 293.77 APE67-dihe-in -66.71, -13.82 -39.44, -53.02 APE12-dist-in 11.6834 APE11-dist-in 11.1202 APE10-dist-in 7.1219 APE9-dist-in 3.1464 None TPO180,PTR182 TPO180,PTR182 XRAY 2.594 0.207 0.255 B 372.0 337.0 0 25 25 0 [[25, 308]] 1.0 4myg Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 8X23A O15264 1 351 365.0 No_ligand No_ligand Inactive DFGin 4.4605 14.5711 BLBplus -108.75, 159.38 60.92, 31.98 -79.48, 152.86 61.29, 91.31 76.91, 8.49 in-out in 9.5785 Saltbr-out 4.1387 HRD-in -79.23, -65.19 81.95, -11.45 out-out-out SNCooo out-out ActLoopNT-out 9.1781 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -142.17, 156.6 APE9-dihe-na -74.19, 163.51 APE8-dihe-in -63.49, 139.71 APE8-rot-out 62.01 APE67-dihe-in -59.97, -27.66 -138.08, 36.98 APE12-dist-out 24.2187 APE11-dist-out 22.0117 APE10-dist-out 18.5952 APE9-dist-out 12.1473 None None None XRAY 1.5 0.126 0.171 A 352.0 345.0 6 25 19 6 [[25, 308]] 1.0 8x23 Homo sapiens CMGC_MAPK13_HUMAN CMGC 2.8e-83 285.6 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 4YNOA O15264 2 351 365.0 No_ligand No_ligand Inactive DFGin 4.6408 14.5292 BLBplus -106.91, 159.82 58.83, 35.45 -83.62, 151.39 56.12, 89.43 75.59, 13.44 in-out in 9.5181 Saltbr-out 4.1995 HRD-in -78.84, -61.56 81.3, -14.44 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na 178.94, 64.59 APE9-dihe-na -68.07, 151.86 APE8-dihe-in -68.05, 140.16 APE8-rot-out 60.48 APE67-dihe-in -55.99, -28.21 -137.84, 31.53 APE12-dist-out 16.68 APE11-dist-out 20.618 APE10-dist-out 21.3409 APE9-dist-out 12.3543 None None None XRAY 1.7 0.198 0.225 A 371.0 342.0 8 25 17 8 [[25, 308]] 1.0 4yno Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 3COIA O15264 2 351 365.0 No_ligand No_ligand Inactive DFGin 5.1434 14.696 BLBplus -109.34, 158.38 67.06, 25.75 -76.24, 161.57 53.14, 88.16 69.14, 9.53 in-out in 9.3045 Saltbr-out 4.9944 HRD-in -80.05, -63.36 75.96, -9.38 out-out-out SNCooo out-out ActLoopNT-out 7.8488 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_nnoo APE10-dihe-na 999.0, -33.58 APE9-dihe-na -115.96, 123.69 APE8-dihe-out -119.11, -9.86 APE8-rot-out 59.12 APE67-dihe-out -113.05, 116.37 -126.84, 125.76 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 17.0322 APE9-dist-out 12.4015 None None None XRAY 2.09 0.208 0.242 A 353.0 342.0 8 25 17 8 [[25, 308]] 1.0 3coi Homo sapiens CMGC_MAPK13_HUMAN CMGC 5.4e-83 284.6 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 4EYMA O15264 2 351 365.0 0RX:401 Type1 Inactive DFGin 4.589 14.2596 BLBplus -111.28, 160.93 55.5, 39.7 -81.9, 162.64 49.72, 96.13 62.24, 29.05 in-in in 8.615 Saltbr-in 2.6388 HRD-in -72.75, -50.15 76.19, -24.88 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nooo APE10-dihe-na 173.31, 74.82 APE9-dihe-na -69.52, 150.13 APE8-dihe-in -65.84, 135.62 APE8-rot-out 59.45 APE67-dihe-in -54.22, -31.49 -134.06, 34.95 APE12-dist-none 999.0 APE11-dist-out 18.9199 APE10-dist-out 19.5099 APE9-dist-out 12.2283 None None None XRAY 2.353 0.206 0.269 A 371.0 340.0 10 25 15 10 [[25, 308]] 1.0 4eym Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 5EKOA O15264 2 351 365.0 N17:401 Type1 Inactive DFGin 4.5273 14.3954 BLBplus -108.72, 155.21 64.28, 36.89 -82.97, 147.4 52.85, 91.53 75.52, 26.34 in-in in 8.5872 Saltbr-in 2.9082 HRD-in -83.1, -57.5 81.13, -16.86 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_oooo APE10-dihe-na -120.45, 66.93 APE9-dihe-na -76.58, 149.26 APE8-dihe-in -66.62, 135.73 APE8-rot-out 63.55 APE67-dihe-in -58.79, -27.08 -132.32, 34.84 APE12-dist-out 15.349 APE11-dist-out 18.9116 APE10-dist-out 21.0131 APE9-dist-out 12.2945 None None None XRAY 2.0 0.202 0.241 A 371.0 341.0 9 25 16 9 [[25, 308]] 1.0 5eko Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 4EYJA O15264 2 351 365.0 N61:401 Type2 Inactive DFGout 14.1412 8.9259 BBAminus -119.65, 169.45 -144.66, 93.65 -66.01, -22.87 246.34, 91.33 167.61, -135.3 in-in in 8.5521 Saltbr-in 2.6928 HRD-in -79.04, -51.35 75.59, -22.68 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 159.84 APE8-dihe-in -78.63, 140.7 APE8-rot-out 65.75 APE67-dihe-in -60.46, -26.97 -136.66, 39.73 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.5083 None None None XRAY 2.102 0.244 0.275 A 371.0 338.0 12 25 13 12 [[25, 308]] 1.0 4eyj Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13
MAPK13 MK13_HUMAN 5EKNA O15264 2 351 365.0 N58:401 Type2 Inactive DFGout 13.7266 11.5016 None -126.43, 178.01 -163.99, 148.16 -168.34, 999.0 22.62, 60.64 999.0, 999.0 in-in in 8.9624 Saltbr-in 3.1478 HRD-in -73.93, -48.48 70.17, -10.09 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 128.38 APE8-dihe-in -75.44, 122.66 APE8-rot-out 69.9 APE67-dihe-in -66.29, -24.17 -132.85, 41.66 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.6621 None None None XRAY 2.594 0.22 0.273 A 371.0 336.0 14 25 11 14 [[25, 308]] 1.0 5ekn Homo sapiens CMGC_MAPK13_HUMAN CMGC 3.4e-83 285.3 4.0 301.0 298.0 167 168 169 171 173 54 72 76 147 149 148 150.0 205 192 187 186 185 184 183 182 181 108 Mitogen-activated protein kinase 13

CMGC_MAPK13 (Mitogen-activated protein kinase 13)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name