STE_MAP3K2 (Mitogen-activated protein kinase kinase kinase 2)

Total number of chains: 4
Active chains: 2
Uniprot: M3K2_HUMAN
Kinase Domain Residues: 356 - 616
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q9Y2U5-K1A
DFGout BBAminus 1 25.0% 9P6AA
DFGout None 1 25.0% 9P6AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
AF-Q9Y2U5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 348 - 619 0 None None Mitogen-activated protein kinase kinase kinase 2
AF-Q9Y2U5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 348 - 619 0 None None Mitogen-activated protein kinase kinase kinase 2
9P6AA 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 0LI Type2 351 - 617 0 None None Mitogen-activated protein kinase kinase kinase 2
9P6AB 2.4 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnoo 0LI Type2 347 - 618 0 None None Mitogen-activated protein kinase kinase kinase 2

STE_MAP3K2 (Mitogen-activated protein kinase kinase kinase 2)

Total number of chains: 4
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% AF-Q9Y2U5-K1A
DFGout BBAminus 1 25.0% 9P6AA
DFGout None 1 25.0% 9P6AB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
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UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
M3K2_HUMAN AF-Q9Y2U5-K1A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 348 - 619 0 None None Mitogen-activated protein kinase kinase kinase 2 Homo sapiens
M3K2_HUMAN AF-Q9Y2U5-K3A -1.0 Active DFGin‑BLAminus in-in in-in nonTYR APEdihe_aaiii APEdist_iiii No_ligand No_ligand 348 - 619 0 None None Mitogen-activated protein kinase kinase kinase 2 Homo sapiens
M3K2_HUMAN 9P6AA 2.4 Inactive DFGout‑BBAminus in-in none-out nonTYR APEdihe_aaioi APEdist_oooo 0LI Type2 351 - 617 0 None None Mitogen-activated protein kinase kinase kinase 2 Homo sapiens
M3K2_HUMAN 9P6AB 2.4 Inactive DFGout‑None in-in none-out nonTYR APEdihe_aaioi APEdist_nnoo 0LI Type2 347 - 618 0 None None Mitogen-activated protein kinase kinase kinase 2 Homo sapiens

STE_MAP3K2 (Mitogen-activated protein kinase kinase kinase 2)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Download database table as tsv Go to Advanced Page
UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism