TYR_FGR (Tyrosine-protein kinase Fgr)

Total number of chains: 5
Active chains: 2
Uniprot: FGR_HUMAN
Kinase Domain Residues: 263 - 514
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 40.0% AF-P09769-K1A
DFGin BLBplus 2 40.0% 7UY0A
DFGout None 1 20.0% 7UY3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FGR AF-P09769-K1A P09769 255 522 529.0 No_ligand No_ligand Active DFGin 6.3053 13.7831 BLAminus -131.22, -174.54 50.84, 67.52 -79.69, 14.04 299.78, 96.16 -58.52, -33.61 in-in in 7.8659 Saltbr-in 2.632 HRD-in -86.03, -47.79 65.95, 4.85 in-in-in SNCiii in-in ActLoopNT-in 2.9333 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.95, 132.36 APE9-dihe-in -120.58, 155.7 APE8-dihe-in -73.03, 83.95 APE8-rot-na 31.77 APE67-dihe-in -71.27, -18.45 -39.68, -37.5 APE12-dist-na 14.8613 APE11-dist-na 10.0569 APE10-dist-na 12.4708 APE9-dist-in 6.5401 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[263, 514]] 1.0 AF-P09769-K1 TYR_FGR_HUMAN TYR 7.4e-90 306.7 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR AF-P09769-K3A P09769 255 522 529.0 No_ligand No_ligand Active DFGin 5.9413 13.9332 BLAminus -139.29, 179.96 57.9, 58.48 -70.47, 12.32 297.79, 91.4 -59.01, -29.8 in-in in 8.0457 Saltbr-in 2.669 HRD-in -89.32, -45.36 66.41, -5.22 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.92, 119.91 APE9-dihe-in -129.55, 159.67 APE8-dihe-in -77.45, 79.27 APE8-rot-na 37.35 APE67-dihe-in -69.3, -5.24 -42.07, -42.83 APE12-dist-na 12.9666 APE11-dist-na 8.3123 APE10-dist-na 9.7947 APE9-dist-in 5.2764 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[263, 514]] 1.0 AF-P09769-K3 TYR_FGR_HUMAN TYR 7.4e-90 306.7 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR 7UY0A P09769 80 527 529.0 VSE:60603 Type1.5_Back Inactive DFGin 5.7348 12.7912 BLBplus -121.88, 169.34 64.12, 34.21 -88.77, 150.89 41.84, 81.29 77.32, -34.65 out-out out 14.1569 Saltbr-out 14.7413 HRD-in -71.29, -57.87 80.99, -12.74 out-out-in SNCooi out-in ActLoopNT-out 7.3378 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -84.17, 154.88 APE9-dihe-in -155.35, 150.07 APE8-dihe-in -76.33, 114.68 APE8-rot-na 28.2 APE67-dihe-in -70.45, -11.61 -54.93, -52.92 APE12-dist-na 12.3751 APE11-dist-na 9.2674 APE10-dist-na 9.3486 APE9-dist-in 4.6055 Q524E,P525E,G526I,D527P PTR523 PTR523 XRAY 2.55 0.188 0.223 A 456.0 448.0 0 29 29 0 [[263, 514]] 1.0 7uy0 TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR 7UY0B P09769 80 527 529.0 VSE:60602 Type1.5_Back Inactive DFGin 6.1063 12.6131 BLBplus -125.52, 166.09 63.13, 24.52 -73.67, 147.71 43.81, 89.0 68.88, -3.37 out-out out 14.0186 Saltbr-out 15.0732 HRD-in -83.21, -52.86 79.08, -5.23 out-out-out SNCooo out-out ActLoopNT-out 7.0196 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -114.65, 50.51 APE9-dihe-in -76.2, 134.42 APE8-dihe-in -79.6, 70.01 APE8-rot-na 33.47 APE67-dihe-in -61.42, -21.25 -59.06, -43.28 APE12-dist-na 14.5248 APE11-dist-na 17.4805 APE10-dist-na 14.3722 APE9-dist-out 8.403 Q524E,P525E,G526I,D527P PTR523 CME338,PTR523 XRAY 2.55 0.188 0.223 B 456.0 448.0 0 29 29 0 [[263, 514]] 1.0 7uy0 TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR 7UY3A P09769 135 527 529.0 OJL:60601 Type2 Inactive DFGout 13.3727 9.4405 None -141.8, 174.6 -159.04, 146.65 -135.72, 155.25 304.03, 94.95 67.54, 57.31 in-in in 7.4064 Saltbr-in 2.6979 HRD-in -90.25, -41.62 73.25, -18.42 in-out-none SNCion out-none ActLoopNT-out 12.9369 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 151.41 APE8-dihe-in -68.73, 121.25 APE8-rot-na 24.28 APE67-dihe-in -72.57, -4.34 -69.16, -45.43 APE12-dist-na 11.4331 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6062 Q524E,P525E,G526I,D527P PTR523 PTR523 XRAY 2.99 0.207 0.247 A 456.0 386.0 2 29 27 2 [[263, 514]] 1.0 7uy3 TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr

TYR_FGR (Tyrosine-protein kinase Fgr)

Total number of chains: 5
Active chains: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 40.0% AF-P09769-K1A
DFGin BLBplus 2 40.0% 7UY0A
DFGout None 1 20.0% 7UY3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
FGR FGR_HUMAN AF-P09769-K1A P09769 255 522 529.0 No_ligand No_ligand Active DFGin 6.3053 13.7831 BLAminus -131.22, -174.54 50.84, 67.52 -79.69, 14.04 299.78, 96.16 -58.52, -33.61 in-in in 7.8659 Saltbr-in 2.632 HRD-in -86.03, -47.79 65.95, 4.85 in-in-in SNCiii in-in ActLoopNT-in 2.9333 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -109.95, 132.36 APE9-dihe-in -120.58, 155.7 APE8-dihe-in -73.03, 83.95 APE8-rot-na 31.77 APE67-dihe-in -71.27, -18.45 -39.68, -37.5 APE12-dist-na 14.8613 APE11-dist-na 10.0569 APE10-dist-na 12.4708 APE9-dist-in 6.5401 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[263, 514]] 1.0 AF-P09769-K1 Homo sapiens TYR_FGR_HUMAN TYR 7.4e-90 306.7 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR FGR_HUMAN AF-P09769-K3A P09769 255 522 529.0 No_ligand No_ligand Active DFGin 5.9413 13.9332 BLAminus -139.29, 179.96 57.9, 58.48 -70.47, 12.32 297.79, 91.4 -59.01, -29.8 in-in in 8.0457 Saltbr-in 2.669 HRD-in -89.32, -45.36 66.41, -5.22 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.92, 119.91 APE9-dihe-in -129.55, 159.67 APE8-dihe-in -77.45, 79.27 APE8-rot-na 37.35 APE67-dihe-in -69.3, -5.24 -42.07, -42.83 APE12-dist-na 12.9666 APE11-dist-na 8.3123 APE10-dist-na 9.7947 APE9-dist-in 5.2764 None None None AF2 -1.0 1.0 1.0 A 268.0 268.0 0 29 29 0 [[263, 514]] 1.0 AF-P09769-K3 Homo sapiens TYR_FGR_HUMAN TYR 7.4e-90 306.7 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR FGR_HUMAN 7UY0A P09769 80 527 529.0 VSE:60603 Type1.5_Back Inactive DFGin 5.7348 12.7912 BLBplus -121.88, 169.34 64.12, 34.21 -88.77, 150.89 41.84, 81.29 77.32, -34.65 out-out out 14.1569 Saltbr-out 14.7413 HRD-in -71.29, -57.87 80.99, -12.74 out-out-in SNCooi out-in ActLoopNT-out 7.3378 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -84.17, 154.88 APE9-dihe-in -155.35, 150.07 APE8-dihe-in -76.33, 114.68 APE8-rot-na 28.2 APE67-dihe-in -70.45, -11.61 -54.93, -52.92 APE12-dist-na 12.3751 APE11-dist-na 9.2674 APE10-dist-na 9.3486 APE9-dist-in 4.6055 Q524E,P525E,G526I,D527P PTR523 PTR523 XRAY 2.55 0.188 0.223 A 456.0 448.0 0 29 29 0 [[263, 514]] 1.0 7uy0 Homo sapiens TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR FGR_HUMAN 7UY0B P09769 80 527 529.0 VSE:60602 Type1.5_Back Inactive DFGin 6.1063 12.6131 BLBplus -125.52, 166.09 63.13, 24.52 -73.67, 147.71 43.81, 89.0 68.88, -3.37 out-out out 14.0186 Saltbr-out 15.0732 HRD-in -83.21, -52.86 79.08, -5.23 out-out-out SNCooo out-out ActLoopNT-out 7.0196 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -114.65, 50.51 APE9-dihe-in -76.2, 134.42 APE8-dihe-in -79.6, 70.01 APE8-rot-na 33.47 APE67-dihe-in -61.42, -21.25 -59.06, -43.28 APE12-dist-na 14.5248 APE11-dist-na 17.4805 APE10-dist-na 14.3722 APE9-dist-out 8.403 Q524E,P525E,G526I,D527P PTR523 CME338,PTR523 XRAY 2.55 0.188 0.223 B 456.0 448.0 0 29 29 0 [[263, 514]] 1.0 7uy0 Homo sapiens TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr
FGR FGR_HUMAN 7UY3A P09769 135 527 529.0 OJL:60601 Type2 Inactive DFGout 13.3727 9.4405 None -141.8, 174.6 -159.04, 146.65 -135.72, 155.25 304.03, 94.95 67.54, 57.31 in-in in 7.4064 Saltbr-in 2.6979 HRD-in -90.25, -41.62 73.25, -18.42 in-out-none SNCion out-none ActLoopNT-out 12.9369 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 151.41 APE8-dihe-in -68.73, 121.25 APE8-rot-na 24.28 APE67-dihe-in -72.57, -4.34 -69.16, -45.43 APE12-dist-na 11.4331 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.6062 Q524E,P525E,G526I,D527P PTR523 PTR523 XRAY 2.99 0.207 0.247 A 456.0 386.0 2 29 27 2 [[263, 514]] 1.0 7uy3 Homo sapiens TYR_FGR_HUMAN TYR 4e-89 304.4 1.0 260.0 260.0 399 400 401 403 405 291 306 310 379 381 380 382.0 440 428 423 422 421 420 419 418 417 335 Tyrosine-protein kinase Fgr

TYR_FGR (Tyrosine-protein kinase Fgr)

Total number of chains: 0
Active chains: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name