AF-Q9NWZ3-K1

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 167 - 460 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       176        186        196        206 
SFSFYELKNV TNNFDERPIS VGGNKMGEGG FGVVYKGYVN 
       216        226        236        246 
NTTVAVKKLA AMVDITTEEL KQQFDQEIKV MAKCQHENLV 
       256        266        276        286 
ELLGFSSDGD DLCLVYVYMP NGSLLDRLSC LDGTPPLSWH 
       296        306        316        326 
MRCKIAQGAA NGINFLHENH HIHRDIKSAN ILLDEAFTAK 
       336        346        356        366 
ISDFGLARAS EKFAQTVMTS RIVGTTAYMA PEALRGEITP 
       376        386        396        406 
KSDIYSFGVV LLEIITGLPA VDEHREPQLL LDIKEEIEDE 
       416        426        436        446 
EKTIEDYIDK KMNDADSTSV EAMYSVASQC LHEKKNKRPD 
       456 
IKKVQQLLQE MTAS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None