AF-Q5S007-K1

LRRK2 (Leucine-rich repeat serine/threonine-protein kinase 2)
Group: TKL
Uniprot: LRRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 1875 - 2134
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 1867 - 2142 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1876       1886       1896       1906 
NIMLNNDELE FEQAPEFLLG DGSFGSVYRA AYEGEEVAVK 
      1916       1926       1936       1946 
IFNKHTSLRL LRQELVVLCH LHHPSLISLL AAGIRPRMLV 
      1956       1966       1976       1986 
MELASKGSLD RLLQQDKASL TRTLQHRIAL HVADGLRYLH 
      1996       2006       2016       2026 
SAMIIYRDLK PHNVLLFTLY PNAAIIAKIA DYGIAQYCCR 
      2036       2046       2056       2066 
MGIKTSEGTP GFRAPEVARG NVIYNQQADV YSFGLLLYDI 
      2076       2086       2096       2106 
LTTGGRIVEG LKFPNEFDEL EIQGKLPDPV KEYGCAPWPM 
      2116       2126       2136 
VEKLIKQCLK ENPQERPTSA QVFDILNSAE LVCLTR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None