AF-Q12852-K1

MAP3K12 (Mitogen-activated protein kinase kinase kinase 12)
Group: TKL
Uniprot: M3K12_HUMAN
Organism: Homo sapiens
Domain boundary: 125 - 366
Resolu: -1.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 117 - 374 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       126        136        146        156 
LWEVPFEEIL DLQWVGSGAQ GAVFLGRFHG EEVAVKKVRD 
       166        176        186        196 
LKETDIKHLR KLKHPNIITF KGVCTQAPCY CILMEFCAQG 
       206        216        226        236 
QLYEVLRAGR PVTPSLLVDW SMGIAGGMNY LHLHKIIHRD 
       246        256        266        276 
LKSPNMLITY DDVVKISDFG TSKELSDKST KMSFAGTVAW 
       286        296        306        316 
MAPEVIRNEP VSEKVDIWSF GVVLWELLTG EIPYKDVDSS 
       326        336        346        356 
AIIWGVGSNS LHLPVPSSCP DGFKILLRQC WNSKPRNRPS 
       366 
FRQILLHLDI ASADVLST
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None