8S3X

LIMK2 (LIM domain kinase 2)
Group: TKL
Uniprot: LIMK2_HUMAN
Organism: Homo sapiens
Domain boundary: 331 - 603
Resolu: 2.59

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-none out-out A1H41 Type1 334 - 631 21
B Inactive DFGin BLBplus out-none out-out A1H41 Type1 330 - 631 24
C Inactive DFGin BLBplus out-out out-out A1H41 Type1 330 - 631 25
D Inactive DFGin BLBplus out-none out-out A1H41 Type1 331 - 631 26
Representative sequence - Chain D
337 347 357 367
smdLIHGEVL GKGFFGQAIK VThkatgkVM VMKELIrcDE
377 387 397 407
ETQKTFLTEV KVMRSLDHPN VLKFIGVLYK DKKLNLLTEY
417 427 437 447
IEGGTLKDFL RSMdpFPWQQ KVRFAKGIAS GMAYLHSMCI
457 467 477 487
IHRDLNSHNC LIKLDKTVVV ADFGLSRLIv eerkrapmek
497 507 517 527
attkkrtlrk ndrkkRYTVV GNPYWMAPEM LNGKSYDETV
537 547 557 567
DIFSFGIVLC EIIGQVYADP DCLPRTLDFG LNVKLFWEKF
577 587 597 607
VPTDCPPAFF PLAAICCRLE PESRPAFSKL EDSFEALSLY
617 627
LgeLGIPLPA ELEELDHTVS MQYGl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None