8P4Z

CDK7 (Cyclin-dependent kinase 7)
Group: CMGC
Uniprot: CDK7_HUMAN
Organism: Homo sapiens
Domain boundary: 12 - 296
Resolu: 2.75

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus out-out out-out WZ8 Type1 11 - 310 13
B Inactive DFGin BLBplus out-out out-out WZ8 Type1 10 - 310 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        17         27         37         47 
gPKRYEKLDF LGEGQFATVY KARDKNTNQI VAIKKIKLGh 
        57         67         77         87 
rseakdgiNR TALREIKLLQ ELSHPNIIGL LDAFGhksNI 
        97        107        117        127 
SLVFDFMETD LEVIIKDNSL VLTPSHIKAY MLMTLQGLEY 
       137        147        157        167 
LHQHWILHRD LKPNNLLLDE NGVLKLADFG LAKSfgspnr 
       177        187        197        207 
aythqvVTRW YRAPELLFGA RMYGVGVDMW AVGCILAELL 
       217        227        237        247 
LRVPFLPGDS DLDQLTRIFE TLGTPTEEQW PDMCSLPDYV 
       257        267        277        287 
TFKSFPGIPL HHIFSAAGDD LLDLIQGLFL FNPCARITAT 
       297        307 
QALKMKYFSN RPGPTPGCQL PRPn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None