8HLT

DYRK2 (Dual specificity tyrosine-phosphorylation-regulated kinase 2)
Group: CMGC
Uniprot: DYRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 222 - 535
Resolu: 2.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in XSE Type1 151 - 535 0
B Inactive DFGin None in-in in-in XSE Type1 151 - 537 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       154        164        174        184 
gmgkvkATPM TPEQAMKQYM QKLTAFEHHE IFSYPEIYFL 
       194        204        214        224 
GLNAKKRQGM TGGPNNGGYD DDQGSYVQVP HDHVAYRYEV 
       234        244        254        264 
LKVIGKGSFG QVVKAYDHKV HQHVALKMVR NEKRFHRQAA 
       274        284        294        304 
EEIRILEHLR KQDKDNTMNV IHMLENFTFR NHICMTFELL 
       314        324        334        344 
SMNLYELIKK NKFQGFSLPL VRKFAHSILQ CLDALHKNRI 
       354        364        374        384 
IHCDLKPENI LLKQQGRSGI KVIDFGSSCY EHQRVYTYIQ 
       394        404        414        424 
SRFYRAPEVI LGARYGMPID MWSLGCILAE LLTGYPLLPG 
       434        444        454        464 
EDEGDQLACM IELLGMPSQK LLDASKRAKN FVSSKGYPRY 
       474        484        494        504 
CTVTTLSDGS VVLNGGRSRR GKLRGPPESR EWGNALKGCD 
       514        524        534 
DPLFLDFLKQ CLEWDPAVRM TPGQALRHPW LRR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X382