8GW3

MAP3K7 (Mitogen-activated protein kinase kinase kinase 7)
Group: TKL
Uniprot: M3K7_HUMAN
Organism: Homo sapiens
Domain boundary: 36 - 286
Resolu: 2.05

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out out-out No_ligand No_ligand 27 - 497 0
B Inactive DFGinter None out-out out-out No_ligand No_ligand 27 - 497 0
C Inactive DFGinter None out-none none-out No_ligand No_ligand 25 - 497 3
D Inactive DFGinter None out-out none-out No_ligand No_ligand 27 - 495 3
Representative sequence - Chain D
24 34 44 54
agemieapsq vlNFEEIDYK EIEVEEVVGR GAFGVVCKAK
64 74 84 94
WRAKDVAIKQ IESESERKAF IVELRQLSRV NHPNIVKLYG
104 114 124 134
ACLNPVCLVM EYAEGGSLYN VLHGAEPLPY YTAAHAMSWC
144 154 164 174
LQCSQGVAYL HSMQPKALIH RDLKPPNLLL VAGGTVLKIC
184 194 204 214
DFGTacdIQT HMTNNKGSAA WMAPEVFEGS NYSEKCDVFS
224 234 244 254
WGIILWEVIT RRKPFDEIGG PAFRIMWAVH NGTRPPLIKN
264 274 284 294
LPKPIESLMT RCWSKDPSQR PSMEEIVKIM THLMRYFPGA
468 478 488 498
DEPLQYPCQh slppgedGRV EPYVDFAEFY RLWSVDHgeq

svvtap
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None