8DEG

MAP3K12 (Mitogen-activated protein kinase kinase kinase 12)
Group: TKL
Uniprot: M3K12_HUMAN
Organism: Homo sapiens
Domain boundary: 125 - 366
Resolu: 2.79

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out none-out SIQ Type1 117 - 398 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -        119        129 
ifriihtvpp sgadpgpkra efmgsedLWE VPFEEILDLQ 
       139        149        159        169 
WVGSGAQGAV FLGRFHGEEV AVKKVRDLKE TDIKHLRKLK 
       179        189        199        209 
HPNIITFKGV CTQAPCYCIL MEFCAQGQLY EVLRAGRPVT 
       219        229        239        249 
PSLLVDWSMG IAGGMNYLHL HKIIHRDLKS PNMLITYDDV 
       259        269        279        289 
VKISDFGtsk elsdkstkms faGTVAWMAP EVIRNEPVSE 
       299        309        319        329 
KVDIWSFGVV LWELLTGEIP YKDVDSSAII WGVGSNSLHL 
       339        349        359        369 
PVPSSCPDGF KILLRQCWNS KPRNRPSFRQ ILLHLDIASA 
       379        389        399          - 
DVLSTPQETY FKSQAEWREE VKLHFEKIKs egtgnshhhh 

hh
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None