8CIE

CDKL5 (Cyclin-dependent kinase-like 5)
Group: CMGC
Uniprot: CDKL5_HUMAN
Organism: Homo sapiens
Domain boundary: 13 - 297
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out US0 Type1 13 - 303 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         9         19         29         39 
smkipnignv mnkFEILGVV GEGAYGVVLK CRHKETHEIV 
        49         59         69         79 
AIKKFKdsee neEVKETTLR ELKMLRTLKQ ENIVELKEAF 
        89         99        109        119 
rrrgkLYLVF EYVEKNMLEL LEEMPNGVPP EKVKSYIYQL 
       129        139        149        159 
IKAIHWCHKN DIVHRDIKPE NLLISHNDVL KLCDFGFARN 
       169        179        189        199 
LSEGNNANYD EEVATRWYRS PELLLGAPYG KSVDMWSVGC 
       209        219        229        239 
ILGELSDGQP LFPGESEIDQ LFTIQKVLGP LPSEQMKLFY 
       249        259        269        279 
SNPRFHGLRF PAVNHPQSLE RRYLGILNSV LLDLMKNLLK 
       289        299 
LDPADRYLTE QCLNHPTFQT QRLL
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None