Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 3 | AF-O76039-K1A |
PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|
AF-O76039-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 5 - 305 | None | None | 0 |
4BGQA | 2.0 | None | DFGin | BLAminus | out-out | in-none | 38R | Type1 | 9 - 302 | T169D,Y171E | None | 11 |
8CIEA | 2.2 | Inactive | DFGin | BLAminus | in-in | in-out | US0 | Type1 | 13 - 303 | None | None | 0 |
Spatial | Dihedral | Chains | Representative |
---|---|---|---|
DFGin | BLAminus | 3 | AF-O76039-K1A |
Organism | UniprotID | PDB | Resolution | Activity Label | Spatial Label | Dihedral Label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Mutation | Phosphorylation | Unresolved residues in A-loop |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Homo sapiens | CDKL5_HUMAN | AF-O76039-K1A | -1.0 | Active | DFGin | BLAminus | in-in | in-in | No_ligand | No_ligand | 5 - 305 | None | None | 0 |
Homo sapiens | CDKL5_HUMAN | 4BGQA | 2.0 | None | DFGin | BLAminus | out-out | in-none | 38R | Type1 | 9 - 302 | T169D,Y171E | None | 11 |
Homo sapiens | CDKL5_HUMAN | 8CIEA | 2.2 | Inactive | DFGin | BLAminus | in-in | in-out | US0 | Type1 | 13 - 303 | None | None | 0 |