| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| AAA | Inactive | DFGin | BLAminus | in-out | in-in | R73 | Type1 | 163 - 459 | 4 |
| BBB | Inactive | DFGin | BLAminus | in-out | in-in | R73 | Type1 | 162 - 459 | 5 |
| CCC | Inactive | DFGin | BLAminus | in-out | in-in | R73 | Type1 | 163 - 459 | 6 |
| DDD | Inactive | DFGin | BLAminus | in-out | in-in | R73 | Type1 | 164 - 459 | 4 |
Representative sequence - Chain DDD
171 181 191 201
dtRFHSFSFY ELKNVTNNFD ERPISVGGNK MGEggFGVVY
211 221 231 241
KGYVNNTTVA VKKLAamvdi TTEELKQQFD QEIKVMAKCQ
251 261 271 281
HENLVELLGF SSDGDDLCLV YVYMPNGSLL DRLSCLDGTP
291 301 311 321
PLSWHMRCKI AQGAANGINF LHENHHIHRD IKSANILLDE
331 341 351 361
AFTAKISDFG LARASekfaQ TVMTSRIVGT TAYMAPEALR
371 381 391 401
GEITPKSDIY SFGVVLLEII TGLPAVDEHR EPQLLLDIKE
411 421 431 441
EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS VASQCLHEKK
451
NKRPDIKKVQ QLLQEMTAs