7OPM

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 2.45

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 08G Type1 1 - 360 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         6         16         26         36 
gsASMAAAAA AGAGPEMVRG QVFDVGPRYT NLSYIGEGAY 
        46         56         66         76 
GMVCSAYDNV NKVRVAIKKI SPFEHQTYCQ RTLREIKILL 
        86         96        106        116 
RFRHENIIGI NDIIRAPTIE QMKDVYIVQD LMETDLYKLL 
       126        136        146        156 
KTQHLSNDHI CYFLYQILRG LKYIHSANVL HRDLKPSNLL 
       166        176        186        196 
LNTTCDLKIC DFGLARVADP DHDHTGFLTE YVATRWYRAP 
       206        216        226        236 
EIMLNSKGYT KSIDIWSVGC ILAEMLSNRP IFPGKHYLDQ 
       246        256        266        276 
LNHILGILGS PSQEDLNCII NLKARNYLLS LPHKNKVPWN 
       286        296        306        316 
RLFPNADSKA LDLLDKMLTF NPHKRIEVEQ ALAHPYLEQY 
       326        336        346        356 
YDPSDEPIAE APFKFDMELD DLPKEKLKEL IFEETARFQP 

GYRS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X185,X187