7EJV

DYRK2 (Dual specificity tyrosine-phosphorylation-regulated kinase 2)
Group: CMGC
Uniprot: DYRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 222 - 535
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in YK2 Type1 151 - 537 0
B Inactive DFGin BLAminus in-out in-in YK2 Type1 153 - 543 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       162        172        182        192 
PMTPEQAMKQ YMQKLTAFEH HEIFSYPEIY FLGLNAKKRQ 
       202        212        222        232 
GMTGGPNNGG YDDDQGSYVQ VPHDHVAYRY EVLKVIGKGS 
       242        252        262        272 
FGQVVKAYDH KVHQHVALKM VRNEKRFHRQ AAEEIRILEH 
       282        292        302        312 
LRKQDKDNTM NVIHMLENFT FRNHICMTFE LLSMNLYELI 
       322        332        342        352 
KKNKFQGFSL PLVRKFAHSI LQCLDALHKN RIIHCDLKPE 
       362        372        382        392 
NILLKQQGRS GIKVIDFGSS CYEHQRVYTY IQSRFYRAPE 
       402        412        422        432 
VILGARYGMP IDMWSLGCIL AELLTGYPLL PGEDEGDQLA 
       442        452        462        472 
CMIELLGMPS QKLLDASKRA KNFVSSKGYP RYCTVTTLSD 
       482        492        502        512 
GSVVLNGGRS RRGKLRGPPE SREWGNALKG CDDPLFLDFL 
       522        532        542 
KQCLEWDPAV RMTPGQALRH PWLRRRLPKP P
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X382