7DHC

DYRK2 (Dual specificity tyrosine-phosphorylation-regulated kinase 2)
Group: CMGC
Uniprot: DYRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 222 - 535
Resolu: 2.592

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in H99 Type1 215 - 538 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       224        234        244        254 
HDHVAYRYEV LKVIGKGSFG QVVKAYDHKV HQHVALKMVR 
       264        274        284        294 
NEKRFHRQAA EEIRILEHLR KQDKDNTMNV IHMLENFTFR 
       304        314        324        334 
NHICMTFELL SMNLYELIKK NKFQGFSLPL VRKFAHSILQ 
       344        354        364        374 
CLDALHKNRI IHCDLKPENI LLKQQGRSGI KVIDFGSSCY 
       384        394        404        414 
EHQRVYTYIQ SRFYRAPEVI LGARYGMPID MWSLGCILAE 
       424        434        444        454 
LLTGYPLLPG EDEGDQLACM IELLGMPSQK LLDASKRAKN 
       464        474        484        494 
FVSSKGYPRY CTVTTLSDGS VVLNGGRSRR GKLRGPPESR 
       504        514        524        534 
EWGNALKGCD DPLFLDFLKQ CLEWDPAVRM TPGQALRHPW 

LRRR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X382,X458