7DH3

DYRK2 (Dual specificity tyrosine-phosphorylation-regulated kinase 2)
Group: CMGC
Uniprot: DYRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 222 - 535
Resolu: 2.33

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in H7C Type1 213 - 538 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       222        232        242        252 
VPHDHVAYRY EVLKVIGKGS FGQVVKAYDH KVHQHVALKM 
       262        272        282        292 
VRNEKRFHRQ AAEEIRILEH LRKQDKDNTM NVIHMLENFT 
       302        312        322        332 
FRNHICMTFE LLSMNLYELI KKNKFQGFSL PLVRKFAHSI 
       342        352        362        372 
LQCLDALHKN RIIHCDLKPE NILLKQQGRS GIKVIDFGSS 
       382        392        402        412 
CYEHQRVYTY IQSRFYRAPE VILGARYGMP IDMWSLGCIL 
       422        432        442        452 
AELLTGYPLL PGEDEGDQLA CMIELLGMPS QKLLDASKRA 
       462        472        482        492 
KNFVSSKGYP RYCTVTTLSD GSVVLNGGRS RRGKLRGPPE 
       502        512        522        532 
SREWGNALKG CDDPLFLDFL KQCLEWDPAV RMTPGQALRH 

PWLRRR
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X382,X458