7AKF

DYRK2 (Dual specificity tyrosine-phosphorylation-regulated kinase 2)
Group: CMGC
Uniprot: DYRK2_HUMAN
Organism: Homo sapiens
Domain boundary: 222 - 535
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in RK5 Type1 146 - 535 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -        153        163 
mhhhhhhssg VDLGTENLYF QSMGKVKATP MTPEQAMKQY 
       173        183        193        203 
MQKLTAFEHH EIFSYPEIYF LGLNAKKRQG MTGGPNNGGY 
       213        223        233        243 
DDDQGSYVQV PHDHVAYRYE VLKVIGKGSF GQVVKAYDHK 
       253        263        273        283 
VHQHVALKMV RNEKRFHRQA AEEIRILEHL RKQDKDNTMN 
       293        303        313        323 
VIHMLENFTF RNHICMTFEL LSMNLYELIK KNKFQGFSLP 
       333        343        353        363 
LVRKFAHSIL QCLDALHKNR IIHCDLKPEN ILLKQQGRSG 
       373        383        393        403 
IKVIDFGSSC YEHQRVYTYI QSRFYRAPEV ILGARYGMPI 
       413        423        433        443 
DMWSLGCILA ELLTGYPLLP GEDEGDQLAC MIELLGMPSQ 
       453        463        473        483 
KLLDASKRAK NFVSSKGYPR YCTVTTLSDG SVVLNGGRSR 
       493        503        513        523 
RGKLRGPPES REWGNALKGC DDPLFLDFLK QCLEWDPAVR 
       533        543 
MTPGQALRHP WLrrrlpkpp tgektsvkr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X232,X382,X458