| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGout | None | in-out | out-out | OXW | Type1 | 15 - 320 | 9 |
| B | Inactive | DFGin | BLAminus | in-in | in-out | OXW | Type1 | 16 - 321 | 6 |
| C | None | DFGin | BLAminus | in-in | none-out | OXW | Type1 | 14 - 319 | 14 |
| D | Inactive | DFGinter | None | out-out | out-out | OXW | Type1 | 13 - 321 | 0 |
Representative sequence - Chain D
18 28 38 48
mnihGFDLGS RYMDLKPLGC GGNGLVFSAV DNDCDKRVAI
58 68 78 88
KKIVLTDPQS VKHALREIKI IRRLDHDNIV KVFEILGPSG
98 108 118 128
SQLTDDVGSL TELNSVYIVQ EYMETDLANV LEQGPLLEEH
138 148 158 168
ARLFMYQLLR GLKYIHSANV LHRDLKPANL FINTEDLVLK
178 188 198 208
IGDFGLARIM DPHYSHKGHL SEGLVTKWYR SPRLLLSPNN
218 228 238 248
YTKAIDMWAA GCIFAEMLTG KTLFAGAHEL EQMQLILESI
258 268 278 288
PVVHEEDRQE LLSVIPvyir ndMTEPHKPL TQLLPGISRE
298 308 318
AVDFLEQILT FSPMDRLTAE EALSHPYMSI YSFpmdepi