6UUO

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 3.288

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-none none-out QH1 Type1 450 - 722 14
B Inactive DFGin BLAplus out-out none-out QH1 Type1.5_Back 448 - 721 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       449        459        469        479 
gamdrdssDD WEIPDGQITV GQRIGSgsFG TVYKGKWHGD 
       489        499        509        519 
VAVKMLNVta PTPQQLQAFK NEVGVLRKTR HVNILLFMGY 
       529        539        549        559 
STKPQLAIVT QWCEGSSLYH HLHASETKFE MKKLIDIARQ 
       569        579        589        599 
TARGMDYLHA KSIIHRDLKS NNIFLHEDNT VKIGDFGlat 
       609        619        629        639 
vksrwsgshq feqlsGSILW MAPEVIRMQD SNPYSFQSDV 
       649        659        669        679 
YAFGIVLYEL MTGQLPYSNI NNRDQIIEMV GRGSLSPDLS 
       689        699        709        719 
KVRSNCPKRM KRLMAECLKK KRDERPSFPR ILAEIEELAR 

ELsg
Lower-case residues are disordered in structure.
Mutations: I543A,I544S,I551K,Q562R,L588N,K630S,F667E,Y673S,A688R,L706S,Q709R,S713E,L716E,S720E,P722S,K723G
Phosphorylation: None