| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Active | DFGin | BLAminus | in-in | in-in | KFD | Type1 | 164 - 459 | 4 |
| B | Inactive | DFGin | BLAminus | in-out | in-in | KFD | Type1 | 164 - 459 | 5 |
| C | Active | DFGin | BLAminus | in-in | in-in | KFD | Type1 | 164 - 459 | 4 |
| D | Active | DFGin | BLAminus | in-in | in-in | KFD | Type1 | 164 - 459 | 5 |
Representative sequence - Chain D
173 183 193 203
RFHSFSFYEL KNVTNNFDER PISVGGNKMG EGGFGVVYKG
213 223 233 243
YVNNTTVAVK KLaamvditt eelKQQFDQE IKVMAKCQHE
253 263 273 283
NLVELLGFSS DGDDLCLVYV YMPNGSLLDR LSCLDGTPPL
293 303 313 323
SWHMRCKIAQ GAANGINFLH ENHHIHRDIK SANILLDEAF
333 343 353 363
TAKISDFGLA RASekfaqTV MTSRIVGTTA YMAPEALRGE
373 383 393 403
ITPKSDIYSF GVVLLEIITG LPAVDEHREP QLLLDIKEEI
413 423 433 443
EDEEKTIEDY IDKKMNDADS TSVEAMYSVA SQCLHEKKNK
453
RPDIKKVQQL LQEMTAs