| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Active | DFGin | BLAminus | in-in | in-in | JX4 | Type1 | 164 - 460 | 3 |
| B | Inactive | DFGin | BLAminus | in-out | in-in | JX4 | Type1 | 164 - 459 | 4 |
| C | Active | DFGin | BLAminus | in-in | in-in | JX4 | Type1 | 163 - 460 | 3 |
| D | Inactive | DFGin | BLAminus | in-out | in-in | JX4 | Type1 | 164 - 459 | 0 |
Representative sequence - Chain D
167 177 187 197
gsvsdtRFHS FSFYELKNVT NNFDERPISV GGNKMGEGGF
207 217 227 237
GVVYKGYVNN TTVAVKKLAA MVDITTEELK QQFDQEIKVM
247 257 267 277
AKCQHENLVE LLGFSSDGDD LCLVYVYMPN GSLLDRLSCL
287 297 307 317
DGTPPLSWHM RCKIAQGAAN GINFLHENHH IHRDIKSANI
327 337 347 357
LLDEAFTAKI SDFGLARASE KFAQTVMTSR IVGTTAYMAP
367 377 387 397
EALRGEITPK SDIYSFGVVL LEIITGLPAV DEHREPQLLL
407 417 427 437
DIKEEIEDEE KTIEDYIDKK MNDADSTSVE AMYSVASQCL
447 457
HEKKNKRPDI KKVQQLLQEM TAs