6GES

MAPK3 (Mitogen-activated protein kinase 3)
Group: CMGC
Uniprot: MK03_HUMAN
Organism: Homo sapiens
Domain boundary: 42 - 330
Resolu: 2.07

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 6H3 EWH Type1 Allosteric 25 - 374 0
B Active DFGin BLAminus in-in in-in 6H3 Type1 25 - 374 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         9         19         29         39 
smaaaaaqgg gggeprrteg vgpgvPGEVE MVKGQPFDVG 
        49         59         69         79 
PRYTQLQYIG EGAYGMVSSA YDHVRKTRVA IKKISPFEHQ 
        89         99        109        119 
TYCQRTLREI QILLRFRHEN VIGIRDILRA STLEAMRDVY 
       129        139        149        159 
IVQDLMETDL YKLLKSQQLS NDHICYFLYQ ILRGLKYIHS 
       169        179        189        199 
ANVLHRDLKP SNLLINTTCD LKICDFGLAR IADPEHDHTG 
       209        219        229        239 
FLTEYVATRW YRAPEIMLNS KGYTKSIDIW SVGCILAEML 
       249        259        269        279 
SNRPIFPGKH YLDQLNHILG ILGSPSQEDL NCIINMKARN 
       289        299        309        319 
YLQSLPSKTK VAWAKLFPKS DSKALDLLDR MLTFNPNKRI 
       329        339        349        359 
TVEEALAHPY LEQYYDPTDE PVAEEPFTFA MELDDLPKER 
       369        379 
LKELIFQETA RFQPGvleap
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None