6F3G

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.37

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in CJN Type1 164 - 458 6
B Active DFGin BLAminus in-in in-in CJN Type1 164 - 458 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       173        183        193        203 
RFHSFSFYEL KNVTNNFDER PISVGGNKMG EGGFGVVYKG 
       213        223        233        243 
YVNNTTVAVK KLaamvditT EELKQQFDQE IKVMAKCQHE 
       253        263        273        283 
NLVELLGFSS dgdDLCLVYV YMPNGSLLDR LSCLDGTPPL 
       293        303        313        323 
SWHMRCKIAQ GAANGINFLH ENHHIHRDIK SANILLDEAF 
       333        343        353        363 
TAKISDFGLA RASekfaqtV MTSRIVGTTA YMAPEALRGE 
       373        383        393        403 
ITPKSDIYSF GVVLLEIITG LPAVDEHREP QLLLDIKEEI 
       413        423        433        443 
EDEEKTIEDY IDKKMNDADS TSVEAMYSVA SQCLHEKKNK 
       453 
RPDIKKVQQL LQEMT
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X345,X346