6EGF

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.61

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B Inactive DFGin BLBtrans out-out out-none ANP Type1 164 - 460 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       168        178        188        198 
gamgsRFHSF SFYELKNVTN NFDERPISVG GNKMGEGGFG 
       208        218        228        238 
VVYKGYVNNT TVAVKKLAAM VDITTEELKQ QFDQEIKVMA 
       248        258        268        278 
KCQHENLVEL LGFSSDGDDL CLVYVYMPNG SLLDRLSCLD 
       288        298        308        318 
GTPPLSWHMR CKIAQGAANG INFLHENHHI HRNIKSANIL 
       328        338        348        358 
LDEAFTAKIS DFGLARASEK faqtvmtsri vgTTAYMAPE 
       368        378        388        398 
ALRGEITPKS DIYSFGVVLL EIITGLPAVD EHREPQLLLD 
       408        418        428        438 
IKEEIEDEEK TIEDYIDKKM NDADSTSVEA MYSVASQCLH 
       448        458 
EKKNKRPDIK KVQQLLQEMT AS
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None