6AAM

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 897 - 1176
Resolu: 1.98

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none 9T6 Type1 888 - 1178 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       894        904        914        924 
gpgDPTVFHK RYLKKIRDLG eghfGKVSLY CYDPTNdgTG 
       934        944        954        964 
EMVAVKALka DAGPQHRSGW KQEIDILRTL YHEHIIKYKG 
       974        984        994       1004 
CCEDAGAASL QLVMEYVPLG SLRDYLPRHS IGLAQLLLFA 
      1014       1024       1034       1044 
QQICEGMAYL HAQHYIHRNL AARNVLLDND RLVKIGDFGL 
      1054       1064       1074       1084 
AKAVPeghey yrvredgdsP VFWYAPECLK EYKFYYASDV 
      1094       1104       1114       1124 
WSFGVTLYEL LTHCDSSQSP PTKFLELIGL AQGQMTVLRL 
      1134       1144       1154       1164 
TELLERGERL PRPDKCPAEV YHLMKNCWET EASFRPTFEN 
      1174 
LIPILKTVHE KYQGqaps
Lower-case residues are disordered in structure.
Mutations: C936A,Q969A,E971A,K972A,D1023N,I1114L,C1142A
Phosphorylation: None