5X8I

CLK1 (Dual specificity protein kinase CLK1)
Group: CMGC
Uniprot: CLK1_HUMAN
Organism: Homo sapiens
Domain boundary: 161 - 477
Resolu: 1.902

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in SQZ Type1 154 - 481 0
B Active DFGin BLAminus in-in in-in SQZ Type1 155 - 481 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       156        166        176        186 
mhlicqsgDV LSARYEIVDT LGEGAFGKVV ECIDHKAGGR 
       196        206        216        226 
HVAVKIVKNV DRYCEAARSE IQVLEHLNTT DPNSTFRCVQ 
       236        246        256        266 
MLEWFEHHGH ICIVFELLGL STYDFIKENG FLPFRLDHIR 
       276        286        296        306 
KMAYQICKSV NFLHSNKLTH TDLKPENILF VQSDYTEAYN 
       316        326        336        346 
PKIKRDERTL INPDIKVVDF GSATYDDEHH STLVSTRHYR 
       356        366        376        386 
APEVILALGW SQPCDVWSIG CILIEYYLGF TVFPTHDSKE 
       396        406        416        426 
HLAMMERILG PLPKHMIQKT RKRKYFHHDR LDWDEHSSAG 
       436        446        456        466 
RYVSRACKPL KEFMLSQDVE HERLFDLIQK MLEYDPAKRI 
       476          - 
TLREALKHPF FDLLKksile hhhhhh
Lower-case residues are disordered in structure.
Mutations: R432A
Phosphorylation: None