5V62

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in FRZ AKS Type1 Type1 10 - 360 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        19         29         39         49 
GPEMVRGQVF DVGPRYTNLS YIGEGAYGMV CSAYDNVNKV 
        59         69         79         89 
RVAIKKISPF EHQTYCQRTL REIKILLRFR HENIIGINDI 
        99        109        119        129 
IRAPTIEQMK DVYIVQDLME TDLYKLLKTQ HLSNDHICYF 
       139        149        159        169 
LYQILRGLKY IHSANVLHRD LKPSNLLLNT TCDLKICDFG 
       179        189        199        209 
LARVADPDHD HTGFLTEYVA TRWYRAPEIM LNSKGYTKSI 
       219        229        239        249 
DIWSVGCILA EMLSNRPIFP GKHYLDQLNH ILGILGSPSQ 
       259        269        279        289 
EDLNCIINLK ARNYLLSLPH KNKVPWNRLF PNADSKALDL 
       299        309        319        329 
LDKMLTFNPH KRIEVEQALA HPYLEQYYDP SDEPIAEAPF 
       339        349        359 
KFDMELDDLP KEKLKELIFE ETARFQPGYR S
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X185,X187