5NG3

RIPK2 (Receptor-interacting serine/threonine-protein kinase 2)
Group: TKL
Uniprot: RIPK2_HUMAN
Organism: Homo sapiens
Domain boundary: 18 - 292
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 8 - 297 6
B Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 9 - 297 8
C Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 9 - 297 9
D Inactive DFGin BLBplus out-none out-out No_ligand No_ligand 9 - 297 6
Representative sequence - Chain D
6 16 26 36
gamamngeai csALPTIPYH KLADLRYLSR GASGTVSSAR
46 56 66 76
HADWRVQVAV RHLHIHTPLL DSERKDVLRE AEILHKARFS
86 96 106 116
YILPILGICN EPEFLGIVTE YMPNGSLNEL LHRKTEYPDV
126 136 146 156
AWPLRFRILH EIALGVNYLH NMTPPLLHHD LKTQNILLDN
166 176 186 196
EFHVKIADFG LSKWRMMSLS QSRssksapE GGTIIYMPPE
206 216 226 236
NYEPgqksRA SIKHDIYSYA VITWEVLSRK QPFEDVTNPL
246 256 266 276
QIMYSVSQGH RPVINEESLP YDIPHRARMI SLIESGWAQN
286 296
PDERPSFLKC LIELEPVLRT Feei
Lower-case residues are disordered in structure.
Mutations: K47R
Phosphorylation: X111