5KKR

KSR2 (Kinase suppressor of Ras 2)
MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1)
Pseudokinase
Group: STE TKL
Uniprot: KSR2_HUMAN MP2K1_RABIT
Organism: Oryctolagus cuniculus Homo sapiens
Domain boundary: 68 - 361 666 - 930
Resolution: 3.509

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
C STE MAP2K1 MP2K1_RABIT Dual specificity mitogen-activated protein kinase kinase 1 Oryctolagus cuniculus Inactive DFGin BLBplus out-out out-out No_ligand No_ligand 41 - 381 0
B TKL KSR2 KSR2_HUMAN Kinase suppressor of Ras 2 Homo sapiens Inactive DFGin BLBplus out-none out-out 6U7 Type1.5_Back 650 - 932 5
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       641        651        661        671 
gaemnlslls arsfprkaSQ TSIFLQEWDI PFEQLEIGEL 
       681        691        701        711 
IGkgrFGQVY HGRWHGEVAI RLIDIERDNE DQLKAFKREV 
       721        731        741        751 
MAYRQTRHEN VVLFMGACMS PPHLAIITSL CKGRTLYSVV 
       761        771        781        791 
RDAKIVLDVN KTRQIAQEIV KGMGYLHAKG ILHKDLKSKN 
       801        811        821        831 
VFYDNGKVVI TDFGLFSISG VLQagrreDK LRIQNGWLCH 
       841        851        861        871 
LAPEIIRQLS PDteeDKLPF SKHSDVFALG TIWYELHARE 
       881        891        901        911 
WPFKTQPAEA IIWQMGTGMK PNLSQIGMGK EISDILLFCW 
       921        931        941 
AFEQEERPTF TKLMDMLEKL Pkrnrrlshp ghfwksael
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None