5HVK

LIMK1 (LIM domain kinase 1)
Group: TKL
Uniprot: LIMK1_HUMAN
Organism: Homo sapiens
Domain boundary: 339 - 606
Resolu: 3.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ANP Type1 329 - 634 13
C Inactive DFGin None in-out in-in ANP Type1 329 - 633 14
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
       333        343        353        363 
gamgSRPHRI FRPSDLIHGE VLGKGCFGQA IKVTHRETGE 
       373        383        393        403 
VMVMKELIRF DEETQRTFLK EVKVMRCLEH PNVLKFIGVL 
       413        423        433        443 
YKDKRLNFIT EYIKGGTLRG IIKSMDSQYP WSQRVSFAKD 
       453        463        473        483 
IASGMAYLHS MNIIHRNLNS HNCLVRENKN VVVADFGLAR 
       493        503        513        523 
LMVdektqpe glrslkkPDR KKRYTVVGNP YWMAPEMING 
       533        543        553        563 
RSYDEKVDVF SFGIVLCEII GRVNADPDYL PRTMDFGLNV 
       573        583        593        603 
RGFLDRYCPP NCPPSFFPIT VRCCDLDPEK RPSFVKLEHW 
       613        623        633 
LETLRMHLAG HLPLGPQLEQ LDRGFWETYR rgesg
Lower-case residues are disordered in structure.
Mutations: D460N
Phosphorylation: X508