5HD7

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_RAT
Organism: Rattus norvegicus
Domain boundary: 23 - 311
Resolu: 1.69

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 38Z Type1 9 - 355 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         3         13         23         33 
ahhhhhhmaa aaaagPEMVR GQVFDVGPRY TNLSYIGEGA 
        43         53         63         73 
YGMVCSAYDN LNKVRVAIKK ISPFEHQTYC QRTLREIKIL 
        83         93        103        113 
LRFRHENIIG INDIIRAPTI EQMKDVYIVQ DLMETDLYKL 
       123        133        143        153 
LKTQHLSNDH ICYFLYQILR GLKYIHSANV LHRDLKPSNL 
       163        173        183        193 
LLNTTCDLKI CDFDLARVAD PDHDHTGFLT EYVATRWYRA 
       203        213        223        233 
PEIMLNSKGY TKSIDIWSVG CILAEMLSNR PIFPGKHYLD 
       243        253        263        273 
QLNHILGILG SPSQEDLNCI INLKARNYLL SLPHKNKVPW 
       283        293        303        313 
NRLFPNADSK ALDLLDKMLT FNPHKRIEVE QALAHPYLEQ 
       323        333        343        353 
YYDPSDEPIA EAPFKFDMEL DDLPKEKLKE LIFEETARFQ 

PGyrs
Lower-case residues are disordered in structure.
Mutations: G167D
Phosphorylation: None