5C9C

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 2.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus in-in out-none 4Z5 Type2 449 - 720 16
B Inactive DFGout BBAminus in-in none-none 4Z5 Type2 449 - 720 18
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -        439        449        459 
mdrgshhhhh hgsedrnrmk tlgrrdssdD WEIPDGQITV 
       469        479        489        499 
GQRIGSGSFG TVYKGKWHGD VAVKMLNVTA PTPQQLQAFK 
       509        519        529        539 
NEVGVLRKTR HVNILLFMGY STKPQLAIVT QWCEGSSLYH 
       549        559        569        579 
HLHIIETKFE MIKLIDIARQ TAQGMDYLHA KSIIHRDLKS 
       589        599        609        619 
NNIFLHEDLT VKIGDFGLat eksrwsgshq feqlsgSILW 
       629        639        649        659 
MAPEVIRMqd kNPYSFQSDV YAFGIVLYEL MTGQLPYSNI 
       669        679        689        699 
NNRDQIIFMV GRGYLSPDLS KVRSNCPKAM KRLMAECLKK 
       709        719 
KRDERPLFPQ ILASIELLAR Slpkihr
Lower-case residues are disordered in structure.
Mutations: V600E
Phosphorylation: None