| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Active | DFGin | BLAminus | in-in | in-in | 4S2 | Type1 | 162 - 459 | 3 |
| B | Active | DFGin | BLAminus | in-in | in-in | 4S2 | Type1 | 161 - 459 | 6 |
| C | Inactive | DFGin | BLAminus | in-out | in-in | 4S2 | Type1 | 164 - 460 | 4 |
| D | Active | DFGin | BLAminus | in-in | in-in | 4S2 | Type1 | 164 - 459 | 5 |
Representative sequence - Chain D
169 179 189 199
vsdtRFHSFS FYELKNVTNN FDERPISVGG NKMGEGgFGV
209 219 229 239
VYKGYVNNTT VAVKKLAamv diTTEELKQQ FDQEIKVMAK
249 259 269 279
CQHENLVELL GFSSDGDDLC LVYVYMPNGS LLDRLSCLDG
289 299 309 319
TPPLSWHMRC KIAQGAANGI NFLHENHHIH RDIKSANILL
329 339 349 359
DEAFTAKISD FGLARASekf aqTVMTSRIV GTTAYMAPEA
369 379 389 399
LRGEITPKSD IYSFGVVLLE IITGLPAVDE HREPQLLLDI
409 419 429 439
KEEIEDEEKT IEDYIDKKMN DADSTSVEAM YSVASQCLHE
449 459
KKNKRPDIKK VQQLLQEMTA s