| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGout | BBAminus | out-out | out-in | 4OQ | Type3 | 254 - 542 | 6 |
| B | Inactive | DFGout | BBAminus | out-out | out-in | 4OQ | Type3 | 254 - 540 | 6 |
| C | Inactive | DFGout | BBAminus | out-out | out-out | 4OQ | Type3 | 250 - 541 | 5 |
| D | Inactive | DFGout | BBAminus | out-out | in-out | 4OQ | Type3 | 253 - 541 | 4 |
Representative sequence - Chain D
256 266 276 286
gpsdeeILEK LRSIVSVGDP KKKYTRFEKI GQGASGTVYT
296 306 316 326
AMDVATGQEV AIKQMNlqqq pKKELIINEI LVMRENKNPN
336 346 356 366
IVNYLDSYLV GDELWVVMEY LAGGSLTDVV TETCMDEGQI
376 386 396 406
AAVCRECLQA LEFLHSNQVI HRDIKSDNIL LGMDGSVKLT
416 426 436 446
DFGFcAQITp eqSKRSTMVG TPYWMAPEVV TRKAYGPKVD
456 466 476 486
IWSLGIMAIE MIEGEPPYLN ENPLRALYLI ATNGTPELQN
496 506 516 526
PEKLSAIFRD FLNRCLEMDV EKRGSAKELL QHQFLKIAKP
536
LSSLTPLIAA AKEATknnh