4YHT

BRAF (Serine/threonine-protein kinase B-raf)
Group: TKL
Uniprot: BRAF_HUMAN
Organism: Homo sapiens
Domain boundary: 457 - 716
Resolu: 3.05

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out 4EF Type1 449 - 719 13
B Inactive DFGin BLAminus in-in in-out 4EF Type1 449 - 720 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       458        468        478        488 
DWEIPDGQIT VGQRIGSGSF GTVYKGKWHG DVAVKMLNVT 
       498        508        518        528 
APTPQQLQAF KNEVGVLRKT RHVNILLFMG YSTKPQLAIV 
       538        548        558        568 
TQWCEGSSLY HHLHTNETKF EMTKLIDIAR QTAQGMDYLH 
       578        588        598        608 
AKSIIHRDLK SNNIFLHEDL TVKIGDFGLA TVKSrwsgsh 
       618        628        638        648 
qfeqlsGSIL WMAPEVIRMQ DknPYSFQSD VYAFGIVLYE 
       658        668        678        688 
LMTGQLPYSN INNRDQIIFM VGRGYLSPDL SKVRSNCPKA 
       698        708        718 
MKRLMAECLK KKRDERPTFP QILASIETLA RS
Lower-case residues are disordered in structure.
Mutations: I543T,I544N,I551T,L706T,L716T
Phosphorylation: None