4XJ0

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 2.58

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 41B Type1 12 - 360 0
B Active DFGin BLAminus in-in in-in 41B Type1 12 - 357 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        21         31         41         51 
EMVRGQVFDV GPRYTNLSYI GEGAYGMVCS AYDNVNKVRV 
        61         71         81         91 
AIKKISPFEH QTYCQRTLRE IKILLRFRHE NIIGINDIIR 
       101        111        121        131 
APTIEQMKDV YIVQDLMETD LYKLLKTQHL SNDHICYFLY 
       141        151        161        171 
QILRGLKYIH SANVLHRDLK PSNLLLNTTC DLKICDFGLA 
       181        191        201        211 
RVADPDHDHT GFLTEYVATR WYRAPEIMLN SKGYTKSIDI 
       221        231        241        251 
WSVGCILAEM LSNRPIFPGK HYLDQLNHIL GILGSPSQED 
       261        271        281        291 
lnciinlKAR NYLLSLPHKN KVPWNRLFPN ADSKALDLLD 
       301        311        321        331 
KMLTFNPHKR IEVEQALAHP YLEQYYDPSD EPIAEAPFKF 
       341        351 
DMELDDLPKE KLKELIFEET ARFQPGyrs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None