4W4Y

MAPK10 (Mitogen-activated protein kinase 10)
Group: CMGC
Uniprot: MK10_HUMAN
Organism: Homo sapiens
Domain boundary: 64 - 359
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus out-out out-out 3HQ Type1 45 - 400 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        46         56         66         76 
mamskskvDN QFYSVEVGDS TFTVLKRYQN LKPIGSGAQG 
        86         96        106        116 
IVCAAYDAVL DRNVAIKKLS RPFQNQTHAK RAYRELVLMK 
       126        136        146        156 
CVNHKNIISL LNVFTPQKTL EEFQDVYLVM ELMDANLCQV 
       166        176        186        196 
IQMELDHERM SYLLYQMLCG IKHLHSAGII HRDLKPSNIV 
       206        216        226        236 
VKSDCTLKIL DFGLARTAGT SFMMTPYVVT RYYRAPEVIL 
       246        256        266        276 
GMGYKENVDI WSVGCIMGEM VRHKILFPGR DYIDQWNKVI 
       286        296        306        316 
EQLGTPCPEF MKKLQPTVRN YVENRPKYAG LTFPKLFPDS 
       326        336        346        356 
LFPADSEHNK LKASQARDLL SKMLVIDPAK RISVDDALQH 
       366        376        386        396 
PYINVWYDPA EVEAPPPqiy dkqLDEREHT IEEWKELIYK 

EVMNse
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None