4U97

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.65

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in none-in STU Type1 166 - 458 8
B Inactive DFGin None in-in none-out STU Type1 166 - 458 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       158        168        178        188 
gamgsenksl evsdtrfHSF SFYELKNVTN NFDERPISVG 
       198        208        218        228 
GNKMGEGGFG VVYKGYVNNT TVAVKKLAAm vditteeLKQ 
       238        248        258        268 
QFDQEIKVMA KCQHENLVEL LGFSSDgddL CLVYVYMPNG 
       278        288        298        308 
SLLDRLSCLD GTPPLSWHMR CKIAQGAANG INFLHENHHI 
       318        328        338        348 
HRNIKSANIL LDEAFTAKIS DFglarasek faqtVMTSRI 
       358        368        378        388 
VGTTAYMAPE ALRGEITPKS DIYSFGVVLL EIITGLPAVD 
       398        408        418        428 
EHREPQLLLD IKEEIEDEEK TIEDYIDKKM NDADSTSVEA 
       438        448        458 
MYSVASQCLH EKKNKRPDIK KVQQLLQEMT as
Lower-case residues are disordered in structure.
Mutations: D311N
Phosphorylation: None