4RMZ

IRAK4 (Interleukin-1 receptor-associated kinase 4)
Group: TKL
Uniprot: IRAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 175 - 456
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in T20 Type1 165 - 458 3
B Inactive DFGin BLAminus in-out in-in T20 Type1 165 - 458 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       163        173        183        193 
enkslevsdt rFHSFSFYEL KNVTNNFDER PISVGGNKMG 
       203        213        223        233 
EGGFGVVYKG YVNNTTVAVK KLAamvdITT EELKQQFDQE 
       243        253        263        273 
IKVMAKCQHE NLVELLGFSS DGDDLCLVYV YMPNGSLLDR 
       283        293        303        313 
LSCLDGTPPL SWHMRCKIAQ GAANGINFLH ENHHIHRDIK 
       323        333        343        353 
SANILLDEAF TAKISDFGLA RASekfaqtV MTSRIVGTTA 
       363        373        383        393 
YMAPEALRGE ITPKSDIYSF GVVLLEIITG LPAVDEHREP 
       403        413        423        433 
QLLLDIKEEI EDEEKTIEDY IDKKMNDADS TSVEAMYSVA 
       443        453 
SQCLHEKKNK RPDIKKVQQL LQEMTas
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X342,X345,X346