4RIY

ERBB3 (Receptor tyrosine-protein kinase erbB-3)
EGFR (Epidermal growth factor receptor)
Pseudokinase
Group: TYR
Uniprot: EGFR_HUMAN ERBB3_HUMAN
Organism: Homo sapiens
Domain boundary: 712 - 970 709 - 967
Resolution: 2.981

Chain id Group Gene UniprotID Protein Organism Activity Spatial Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B TYR EGFR EGFR_HUMAN Epidermal growth factor receptor Homo sapiens Inactive DFGin None in-in in-in ADP Type1 688 - 984 4
D TYR EGFR EGFR_HUMAN Epidermal growth factor receptor Homo sapiens Inactive DFGin None in-in in-in ADP Type1 688 - 984 0
A TYR ERBB3 ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 Homo sapiens Inactive DFGin BLBplus out-none out-none ANP Type1 699 - 979 12
C TYR ERBB3 ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 Homo sapiens Inactive DFGin BLBplus out-none out-out ANP Type1 699 - 979 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
       704        714        724        734 
gagkVLARIF KETELRKLKV LGSGVFGTVH KGVWIPEGES 
       744        754        764        774 
IKIPVCIKVI EdksgrqSFQ AVTDHMLAIG SLDHAHIVRL 
       784        794        804        814 
LGLCPGSSLQ LVTQYLPLGS LLDHVRQHRG ALGPQLLLNW 
       824        834        844        854 
GVQIAKGMYY LEEHGMVHRN LAARNVLLKS PSQVQVADFG 
       864        874        884        894 
VADLLPPDDK QLLYSEAKTP IKWMALESIH FGKYTHQSDV 
       904        914        924        934 
WSYGVTVWEL MTFGAEPYAG LRLAEVPDLL EKGGRLAQPQ 
       944        954        964        974 
ICTIDVYMVM VKCWMIDENI RPTFKELANE FTRMARDPPR 
       984        994       1004       1014 
YLVIKresgp giapgpephg ltnkkleeve lepeldldld 

leaeed
Lower-case residues are disordered in structure.
Mutations: E928G
Phosphorylation: None