4QP3

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 2.599

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 36Q Type1 12 - 360 6
B Active DFGin BLAminus in-in in-in 36Q Type1 12 - 357 3
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         1         11         21         31 
mgshhhhhhm aaaaaagagp EmvrGQVFDV GPRYTNLSYI 
        41         51         61         71 
GEGAYGMVCS AYDNVNKVRV AIKKISPFEH QTYCQRTLRE 
        81         91        101        111 
IKILLRFRHE NIIGINDIIR APTIEQMKDV YIVQDLMETD 
       121        131        141        151 
LYKLLKTQHL SNDHICYFLY QILRGLKYIH SANVLHRDLK 
       161        171        181        191 
PSNLLLNTTC DLKICDFGLA RVADPDHDHt gfLTEYVATR 
       201        211        221        231 
WYRAPEIMLN SKGYTKSIDI WSVGCILAEM LSNRPIFPGK 
       241        251        261        271 
HYLDQLNHIL GILGSPsqed lnciINLKAR NYLLSLPHKN 
       281        291        301        311 
KVPWNRLFPN ADSKALDLLD KMLTFNPHKR IEVEQALAHP 
       321        331        341        351 
YLEQYYDPSD EPIAEAPFKF DMELDDLPKE KLKELIFEET 

ARFQPGyrs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None