4K33

FGFR3 (Fibroblast growth factor receptor 3)
Group: TYR
Uniprot: FGFR3_HUMAN
Organism: Homo sapiens
Domain boundary: 472 - 750
Resolu: 2.341

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ACP Type1 459 - 755 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        454        464        474 
mgsshhhhhh sqdpptlanv seleLPADPK WELSRARLTL 
       484        494        504        514 
GKPLGEGAFG QVVMAEAIGI DKDRAAKPVT VAVKMLKDDA 
       524        534        544        554 
TDKDLSDLVS EMEMMKMIGK HKNIINLLGA CTQGGPLYVL 
       564        574        584        594 
VEYAAKGNLR EFLRARRPPG LDYSFDTSkp peEQLTFKDL 
       604        614        624        634 
VSCAYQVARG MEYLASQKCI HRDLAARNVL VTEDNVMKIA 
       644        654        664        674 
DFGLARDVHN LDYYKETTNG RLPVKWMAPE ALFDRVYTHQ 
       684        694        704        714 
SDVWSFGVLL WEIFTLGGSP YPGIPVEELF KLLKEGHRMD 
       724        734        744        754 
KPANCTHDLY MIMRECWHAA PSQRPTFKQL VEDLDRVLTV 

Tstde
Lower-case residues are disordered in structure.
Mutations: C482A,C582S,K650E
Phosphorylation: None