4I5H

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_RAT
Organism: Rattus norvegicus
Domain boundary: 23 - 311
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None in-in out-out G17 Type2 9 - 356 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         9         19         29         39 
snaaaaaagP EMVRGQVFDV GPRYTNLSYI GEGAYGMVCS 
        49         59         69         79 
AYDNLNKVRV AIKKISPFEH QTYCQRTLRE IKILLRFRHE 
        89         99        109        119 
NIIGINDIIR APTIEQMKDV YIVADLMETD LYKLLKTQHL 
       129        139        149        159 
SNDHICYFLY QILRGLKYIH SANVLHRDLK PSNLLLNTTC 
       169        179        189        199 
DLKILDFGLA RVADPdhdht gfLTEYVATR WYRAPEIMLN 
       209        219        229        239 
SKGYTKSIDI WSVGCILAEM LSNRPIFPGK HYLDQLNHIL 
       249        259        269        279 
GILGSPSQED LNCIINLKAR NYLLSLPHKN KVPWNRLFPN 
       289        299        309        319 
ADSKALDLLD KMLTFNPHKR IEVEQALAHP YLEQYYDPSD 
       329        339        349 
EPIAEAPFKf dmeldDLPKE KLKELIFEET ARFQPGYrs
Lower-case residues are disordered in structure.
Mutations: Q103A,C164L
Phosphorylation: None