4H3P

MAPK1 (Mitogen-activated protein kinase 1)
Group: CMGC
Uniprot: MK01_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 313
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out ANP Type1 11 - 359 7
D None DFGin BLAminus in-in in-none ANP Type1 11 - 359 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
         8         18         28         38 
gsmaaaaaag agPEMVRGQV FDVGPRYTNL SYIGEGAYGM 
        48         58         68         78 
VCSAYDNVNK VRVAIKKISP FEHQTYCQRT LREIKILLAF 
        88         98        108        118 
RHENIIGIND IIRAPTIEQM KDVYIVQDLM ETDLYKLLKT 
       128        138        148        158 
QHLSNDHICY FLYQILRGLK YIHSANVLHR DLKPSNLLLN 
       168        178        188        198 
TTCDLKICDF GLARVADPDH dhtgflteyv aTRWYRAPEI 
       208        218        228        238 
MLNSKGYTKS IDIWSVGCIL AEMLSNRPIF PGKHYLDQLN 
       248        258        268        278 
HILGILGSPS QEDLNCIINL KARNYLLSLP HKNKVPWNRL 
       288        298        308        318 
FPNADSKALD LLDKMLTFNP HKRIEVEQAL AHPYLAQYYD 
       328        338        348        358 
PSDEPIAEAP FKFDMELDDL PKEKLKELIF EETARFQPGY 

Rs
Lower-case residues are disordered in structure.
Mutations: R77A,E314A
Phosphorylation: None