4H3B

MAPK10 (Mitogen-activated protein kinase 10)
Group: CMGC
Uniprot: MK10_HUMAN
Organism: Homo sapiens
Domain boundary: 64 - 359
Resolu: 2.08

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus in-in out-out No_ligand No_ligand 45 - 400 0
C Inactive DFGin BLBplus in-in out-out No_ligand No_ligand 45 - 400 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
        54         64         74         84 
DNQFYSVEVG DSTFTVLKRY QNLKPIGSGA QGIVCAAYDA 
        94        104        114        124 
VLDRNVAIKK LSRPFQNQTH AKRAYRELVL MKCVNHKNII 
       134        144        154        164 
SLLNVFTPQK TLEEFQDVYL VMELMDANLC QVIQMELDHE 
       174        184        194        204 
RMSYLLYQML CGIKHLHSAG IIHRDLKPSN IVVKSDCTLK 
       214        224        234        244 
ILDFGLARTA GTSFMMTPYV VTRYYRAPEV ILGMGYKENV 
       254        264        274        284 
DIWSVGCIMG EMVRHKILFP GRDYIDQWNK VIEQLGTPCP 
       294        304        314        324 
EFMKKLQPTV RNYVENRPKY AGLTFPKLFP DSLFPadseh 
       334        344        354        364 
NKLKASQARD LLSKMLVIDP AKRISVDDAL QHPYINVWYD 
       374        384        394 
PAEVEAPPPQ IYDKQLDERE HTIEEWKELI YKEVMN
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None