| Chain id | Activity_label | Spatial_label | Dihedral_label | Chelix-SaltBridge | ActLoopNT-ActLoopCT | Ligand | Type | Residues in structure | Unresolved residues in A-loop |
|---|---|---|---|---|---|---|---|---|---|
| A | Inactive | DFGin | BLAplus | out-out | out-out | T1Q | Type1.5_Back | 448 - 721 | 7 |
| B | Inactive | DFGin | BLAplus | out-out | out-out | T1Q | Type1.5_Back | 448 - 721 | 0 |
Representative sequence - Chain B
- 439 449 459
mdrgshhhhh hgsedrnrmk tlgrrdssDD WEIPDGQITV
469 479 489 499
GQRIGSGSFG TVYKGKWHGD VAVKMLNVTA PTPQQLQAFK
509 519 529 539
NEVGVLRKTR HVNILLFMGY STKPQLAIVT QWCEGSSLYH
549 559 569 579
HLHIIETKFE MIKLIDIARQ TAQGMDYLHA KSIIHRDLKS
589 599 609 619
NNIFLHEDLT VKIGDFGLAT VKSRWSGSHQ FEQLSGSILW
629 639 649 659
MAPEVIRMQD KNPYSFQSDV YAFGIVLYEL MTGQLPYSNI
669 679 689 699
NNRDQIIFMV GRGYLSPDLS KVRSNCPKAM KRLMAECLKK
709 719
KRDERPLFPQ ILASIELLAR SLpkihr