3K54

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 1.94

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus in-out none-out 1N1 Type1 392 - 658 17
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       386        396        406        416 
gplgsknaps taglgYGSWE IDPKDLTFLK ELGTGQFGVV 
       426        436        446        456 
KYGKWRGQYD VAIKMIKEgs msedeFIEEA KVMMNLSHEK 
       466        476        486        496 
LVQLYGVCTK QRPIFIITEY MANGCLLNYL REMRHRFQTQ 
       506        516        526        536 
QLLEMCKDVC EAMEYLESKQ FLHRDLAARN CLVNDQGVVK 
       546        556        566        576 
VSDFGlsryv lddeetssvg skFPVRWSPP EVLMYSKFSS 
       586        596        606        616 
KSDIWAFGVL MWEIYSLGKM PYERFTNSET AEHIAQGLRL 
       626        636        646        656 
YRPHLASEKV YTIMYSCWHE KADERPTFKI LLSNILDVMD 

EEs
Lower-case residues are disordered in structure.
Mutations: Y551E
Phosphorylation: None